Nitric Oxide and the Kidney

Physiology and Pathophysiology

Michael S. Goligorsky, Steven S. Gross (Autoren)

Buch | Hardcover

463 Seiten

1997 | 1997 ed.
Chapman and Hall (Verlag)
978-0-412-08061-6 (ISBN)

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A number of remarkable recent breakthroughs have made the study of nitric oxide one of the most exciting fields in physiology and pathophysiology. The contributors are leading authorites, in most cases the investigators who have pioneered the ideas explored in the book.

A number of remarkable recent breakthroughs have made the study of nitric oxide one of the most exciting fields in physiology and pathophysiology. This authoritative edited volume reviews the progress to date and opens perspectives to novel diagnostic and therapeutic strategies. The contributors are leading authorites, in most cases the investigators who have pioneered the ideas explored in the book.

I. General Biochemistry of NOSs and Cellular Actions of NO.- 1. The Biological Chemistry of NO.- 2. Role of NO and Nitrogen Intermediates in Regulation of Cell Functions.- 3. Nitric Oxide Synthases and Their Cofactors.- 4. Regulation of the NOS Gene Family.- 5. Role of NO in Cell Locomotion.- II. Renal Expression of NOSs and Production of NO.- 6. Metabolic Pathways and Cycles of L-Arginine Synthesis and Utilization.- 7. Distribution of NOSs in the Kidney.- III. NO and the Regulation of Renal Hemodynamics.- 8. Vascular Effects of NO.- 9. Role of NO in the Function of the Juxtaglomerular Apparatus.- 10. NOS in Mesangial Cells: Physiological and Pathophysiological Roles.- 11. Tubuloglomerular Feedback and Macula Densa-Derived NO.- 12. NO and the Renin System.- 13. NO and the Medullary Circulation.- IV. Role of NO system in Renal Pathophysiology.- 14. NO in Septic Shock.- 15. NO and Glomerulonephritis.- 16. NO in Acute Renal Failure.- 17. NO in Diabetic Nephropathy.- 18. NO and Hypertension.- 19. NO in Normal and Preeclamptic Pregnancy.- 20. Sickle Cell Disease and NO.- 21. A Putative Role of NO and Oxidant Injury in the Pathogenesis of Hemolytic Uremic Syndrome.- 22. Role of NO in Urinary Tract Infections.- 23. Role of the NO System in Urinary Tract Obstruction.

Zusatzinfo	XIX, 463 p.
Verlagsort	London
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Nephrologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	0-412-08061-3 / 0412080613
ISBN-13	978-0-412-08061-6 / 9780412080616
Zustand	Neuware