Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics
Springer Berlin (Verlag)
978-3-540-40661-7 (ISBN)
Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses and in developing effective measures of control.
List of Contents.- Reverse Genetics of Mononegavirales.- Reverse Genetics Systems for the Generation of Segmented Negative-Sense RNA Viruses Entirely from Cloned cDNA.- Transcription and Replication of Nonsegmented Negative-Strand RNA Viruses.- Orthomyxovirus Replication, Transcription, and Polyadenylation.- Escaping from the Cell: Assembly and Budding of Negative-Strand RNA Viruses.- Accessory Genes of the Paramyxoviridae, a Large Family of Nonsegmented Negative-Strand RNA Viruses, as a Focus of Active Investigation by Reverse Genetics.- Identification and Characterization of Viral Antagonists of Type I Interferon in Negative-Strand RNA Viruses.- Toward Novel Vaccines and Therapies Based on Negative-Strand RNA Viruses.- Influenza Vaccines Generated by Reverse Genetics.
| Erscheint lt. Verlag | 7.5.2004 |
|---|---|
| Reihe/Serie | Current Topics in Microbiology and Immunology |
| Mitarbeit |
Gast Herausgeber: Yoshihiro Kawaoka |
| Zusatzinfo | IX, 350 p. 27 illus., 3 illus. in color. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 620 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Schlagworte | genes • Genetics • Interferon • Negative Strand RNA Viruses • Paramyxoviridae • Reverse Genetics • RNA • RNS (Ribonukleinsäure) • transcription • Vaccine • Virologie • Virus |
| ISBN-10 | 3-540-40661-1 / 3540406611 |
| ISBN-13 | 978-3-540-40661-7 / 9783540406617 |
| Zustand | Neuware |
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