The Kappa Opioid Receptor

Lee-Yuan Liu-Chen, Saadet Inan (Herausgeber)

Buch | Hardcover

XI, 577 Seiten

2021 | 1st ed. 2022
Springer International Publishing (Verlag)
978-3-030-89073-5 (ISBN)

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This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials.
The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

From the contents. Preface.-Part I: Molecular aspects of KOR.- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals.- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.

Erscheinungsdatum	27.11.2021
Reihe/Serie	Handbook of Experimental Pharmacology
Zusatzinfo	XI, 577 p. 100 illus., 30 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	1107 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Medizin / Pharmazie ► Pharmazie
Schlagworte	Clinical applications of kappa compounds • Kappa opioid receptor • Kappa opioid receptor agonists • Kappa opioid receptor antagonists • Kappa opioid receptor pharmacology • Kor
ISBN-10	3-030-89073-2 / 3030890732
ISBN-13	978-3-030-89073-5 / 9783030890735
Zustand	Neuware