Atopic Dermatitis: Inside Out or Outside In

Lawrence S Chan, Vivian Y. Shi (Herausgeber)

Buch | Hardcover

336 Seiten

2022
Elsevier - Health Sciences Division (Verlag)
978-0-323-84744-5 (ISBN)

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Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etiologies, Atopic Dermatitis: Inside Out or Outside In? examines a myriad of causes that start from both the inside of the body and from the external environment, offering physicians practical ways to design treatments that specifically address these causes. Drs. Lawrence S. Chan and Vivian Y. Shi, along with a team of expert contributing authors, examine the etiology of this complex disorder and provide targeted, comprehensive solutions and the most useful therapeutic plans based on pathophysiology, including evidence-based integrative management.

Analyzes the pathophysiology of atopic dermatitis from two distinct fronts: inside out and outside in-an approach that is unique in the field.
Begins with an overview of the disease, then delves into both internal and external pathogenic factors, followed by the Clinician's Corner, which offers practical recommendations for treatment.
Organizes therapeutic discussions by corresponding pathophysiology rather than a one-size-fits-all approach.
Covers recently FDA-approved and emerging medications, as well as atopic comorbidities.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Dr. Vivian Shi is the Director of Clinical Trials and the Eczema Specialty Clinic at the University of Arkansas for Medical Sciences. Her research and clinical interests are in complex inflammatory skin conditions, skin barrier repair, transepidermal drug delivery, and integrative dermatology. She was an integral part of the team of researchers characterizing the pathophysiology of atopic dermatitis using a transgenic interleukin-4 mouse model of atopic dermatitis. She has published over 150 peer-reviewed articles, and is on the speaker's bureau and the steering committee for the U.S. National Eczema Association and is a faculty member of the International Eczema Council. She has served as the principal investigator for numerous industry-sponsored and investigator-initiated clinical and translational studies in eczematous conditions. She regularly speaks in national and international conferences on atopic dermatitis and inflammatory skin conditions. Additionally, she is the recipient of the several prestigious awards and grants.

Section I: A History of Atopy 1 Historic Perspective 2 Atopy Redefined 3 Atopy of the Skin 4 Epidemiology

Section II: External Factors 5 Skin Barrier 6 Skin and Gut Microbiome 7 Immunogens 8 Nutrition 9 Oxidative Stress, Environmental factors, Pollutants 10 Clinical Evidence: External Factors

Section III: Internal Factors 11 Keratinocytes 12 Microvasculature 13 Humoral Factors 14 Cellular Factors 15 Skin-Gut-Lung Epithelial Permeability 16 Neurosensory Mechanisms 17 Epigenetics 18 Clinical Evidence: Internal Factors

Section IV: Clinician's Corner 19 Therapeutic Guideline Overview 20 Topical Therapies 21 Wound care 22 Skin barrier Repair 23 Emerging Targeted Treatments 24 Microbiome Modulation 25 Itch and Pain Treatments 26 Complementary and Alternative Approaches 1 27 Complementary and Alternative Approaches 2

Erscheinungsdatum	07.04.2022
Verlagsort	Philadelphia
Sprache	englisch
Maße	216 x 276 mm
Gewicht	1130 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
ISBN-10	0-323-84744-7 / 0323847447
ISBN-13	978-0-323-84744-5 / 9780323847445
Zustand	Neuware