The Detection of Biomarkers

Past, Present, and the Future Prospects

Sibel A. Ozkan, Nurgul K. Bakirhan, Fariba Mollarasouli (Herausgeber)

Buch | Softcover

614 Seiten

2021
Academic Press Inc (Verlag)
978-0-12-822859-3 (ISBN)

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Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection.

Prof. Dr. Sibel A. Ozkan is a Full Professor in the Faculty of Pharmacy at Ankara University. She has over 30 years of experience in analytical chemistry. She has established expertise in electrochemistry, validation, electrochemical biosensors, DNA biosensors, enzyme biosensors, biomarkers, drug analysis from biological samples or dosage forms, liquid chromatography, capillary electrophoresis, spectrophotometry. She has won Encouragement Award from Ankara University in 2003, Science Award from Turkish Pharmacists Association in 2008, and The Best Ph.D. Thesis in Turkey Award 2017 (Health Sciences), High Council of Education of Turkey, Ton Duc Thang University “Woman in Science 2019 Prize, 27 December 2019, Ankara University Science Support Award, 2020. Nurgul K. Bakirhan is an Associated Professor at the Department of Analytical Chemistry, Gulhane Faculty of Pharmacy, University of Health Sciences, Turkey. She received her doctorate from the Faculty of Pharmacy at Ankara University in Turkey. She was visiting researcher at the Université libre de Bruxelles with TUBITAK 2214 fellowship during six months. Her research interests include sensors, nanomaterials, conductive polymers, electrochemical impedance spectroscopy and electrochemical investigations on active pharmaceutical compounds, validation. She has published over 60 papers and 10 book chapters. Fariba Mollarasouli is an Assistant Professor in the Department of Chemistry at Yasouj University, Yasouj, Iran. Her areas of research and expertise include analytical and bioanalytical method development, drug analysis, electrochemical sensors and biosensors, immunosensors, as well as the development of various nanomaterials (design, synthesis, characterization, and applications) for fabricating nanosensors with clinical and environmental applications.

1. Introduction to biomarkers 2. Low molecular weight biomarkers: Types and detection strategies 3. Circulating miRNAs as biomarkers for non-invasive cancer diagnosis 4. Cardiac biomarkers: Definition, detection, diagnostic use and efficiency 5. Proteomic-based identification of novel biomarkers 6. Metabolomics tools for biomarker discovery: Applications in Chronic Kidney Disease 7. Electronic devices for biomarker monitoring 8. Novel advances in nanomaterial-based electrochemical sensing of the biomarker 9. Carbon nanomaterials-based electrochemical cancer biomarkers biosensors 10. Optical nanosensors based on SERS substrate for biomedical and biomarker detection applications 11. Optical smartphone-based sensing: Diagnostic of Biomarkers 12. Design of immunosensors for rapid and sensitive detection of biomarkers 13. Recent Advances in immunosensors for Healthcare 14. Impedimetric immunosensors for detection of biomarkers 15. Conducting polymers – versatile tools in analytical systems for the determination of biomarkers and biologically active compounds 16. Molecularly imprinted polymers-based biosensors for sensitive detection of biomarkers 17. Microfluidics technology: past, present and future prospects for biomarker diagnostics 18. Wearable and tattoo biosensors for disease biomarker monitoring 19. Nanomachines and nanorobotics: Improving Cancer Diagnosis and Therapy 20. Analytical Perspective on biomarkers Research: From untargeted to targeted metabolomics

Erscheinungsdatum	17.12.2021
Zusatzinfo	200 illustrations (100 in full color); Illustrations
Verlagsort	San Diego
Sprache	englisch
Maße	216 x 276 mm
Gewicht	1650 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
ISBN-10	0-12-822859-8 / 0128228598
ISBN-13	978-0-12-822859-3 / 9780128228593
Zustand	Neuware