Matrix Metalloproteinases

Buch | Hardcover

362 Seiten

1998
Academic Press Inc (Verlag)
978-0-12-545090-4 (ISBN)

Artikel merken

Covers the structure, regulation, and function of matrix metalloproteinases, and provides information on the strategies to inhibit enzyme activity. This work is intended for investigators with an interest in extracellular matrix biology, matrix turnover, enzymology and biochemistry of proteinases, pathology, and therapeutic interventions.

The chapters in this book thoroughly cover the structure, regulation, and function of matrix metalloproteinases, and provide information on the latest strategies to inhibit enzyme activity. This work will be an indispensable reference tool for investigators with an interest in extracellular matrix biology, matrix turnover, enzymology and biochemistry of proteinases, developmental biology, pathology, and therapeutic interventions.

Contributors.
Preface.
The Matrix Metalloproteinase Family, J.F. Woessner, Jr..
Interstitial Collagenases, J.J. Jeffrey.
Stromelysins 1 and 2, H. Nagase.
72-kDa Gelatinase (Gelatinase A): Structure, Activation, Regulation, and Substrate Specificity, A.E. Yu, A.N. Murphy and W.G. Stetler-Stevenson.
Gelatinase B: Structure, Regulation, and Function, T.H. Vu and Z. Werb.
Matrilysin, C.L. Wilson and L.M. Matrisian.
Macrophage Elastase (MMP-12), S.D. Shapiro and R.M. Senior.
Membrane-Type Matrix Metalloproteinases and Cell Surface-Associated Activation Cascades for Matrix Metalloproteinases, V. Knauper and G. Murphy.
Substrate Specificity and Mechanism of Substrate Recognition of the Matrix Metalloproteinases, V. Imper and H.E. Van Wart.
Synthetic Inhibitors of Matrix Metalloproteinases, P.D. Brown.
Matrix Metalloproteinases in Tissue Repair, W.C. Parks, B.D. Sudbeck, G.R. Doyle and U.K. Saariahlo-Kere.
Regulation of Matrix Metalloproteinase Gene Expression, M.E. Fini, J.R. Cook, R. Mohan and C.E. Brinckerhoff.
Index.

Erscheint lt. Verlag	27.3.1998
Reihe/Serie	Biology of Extracellular Matrix
Mitarbeit	Herausgeber (Serie): Robert P. Mecham
Verlagsort	San Diego
Sprache	englisch
Maße	152 x 229 mm
Gewicht	680 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-12-545090-7 / 0125450907
ISBN-13	978-0-12-545090-4 / 9780125450904
Zustand	Neuware