Practical Oncologic Molecular Pathology

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Buch | Hardcover

XII, 449 Seiten

2021 | 1st ed. 2021
Springer International Publishing (Verlag)
978-3-030-73226-4 (ISBN)

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This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology.
Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.

Yi Ding MD, PhDDepartment of Laboratory Medicine, Diagnostic Medicine InstituteGeisinger HealthDanville, PAUSA
Linsheng Zhang MD, PhDDepartment of Pathology and Laboratory MedicineEmory University School of MedicineAtlanta, GAUSA

The Molecular Pathobiology of Malignant Process and Molecular Diagnostic Testing for Cancer.- Molecular Diagnostic Methods.- Bioinformatics Analysis In Molecular Pathology.- Quality Assurance and Quality Control in Molecular Diagnostic Laboratories.- Breast And Gynecologic Tumors.- Tumors of Central Nervous System.- Lung Cancer.- Gastrointestinal, Hepatobiliary, and Pancreatic Tumors.- Skin Tumors.- Soft Tissue Tumors.- Genitourinary Tumors.- Hereditary Cancer Syndromes and Inherited Cancer Risks.- Acute Myeloid Leukemia.- Myeloproliferative Neoplasms, Myelodysplastic /myeloproliferative Neoplasms and Myelodysplastic Syndromes.- Precursor Lymphoid Neoplasms.- Mature B-Cell Neoplasms.- Plasma Cell Neoplasms.- Mature T- and NK-cell Neoplasms.- Histiocytic and Dendritic Cell Neoplasms.- Bone Marrow Engraftment Analysis.

Erscheinungsdatum	13.07.2021
Reihe/Serie	Practical Anatomic Pathology
Zusatzinfo	XII, 449 p. 192 illus., 181 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	210 x 279 mm
Gewicht	1364 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Schlagworte	Bioinformatics analysis • Breast And Gynecologic System • Molecular Hematopathology • Soft tissue Sarcomas • tumor biology
ISBN-10	3-030-73226-6 / 3030732266
ISBN-13	978-3-030-73226-4 / 9783030732264
Zustand	Neuware