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Manual of Clinical Laboratory Immunology

Buch | Hardcover
1300 Seiten
1997 | 5th Revised edition
American Society for Microbiology (Verlag)
978-1-55581-118-1 (ISBN)
CHF 199,95 inkl. MwSt
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This edition features recent developments on immunological tests and procedures in clinical laboratory immunology. It includes a step-by-step interpretive approach to methodology, with an emphasis on clinical applications and interpretation.
The much-awaited new edition of this classic reference manual features the latest on standard and cutting-edge immunological tests and procedures in clinical laboratory immunology. The best features of earlier editions have remained in this update, including a step-by-step interpretive approach to

PART I: GENERAL METHODS; SECTION A: IMMUNOLOGICAL METHODS; Introduction; Agglutination Immunoassays; Light-Scattering Immunoassays; Enzyme-Linked Immunoassays; A Model System for Radioimmunoassays: Digoxin Reference Method; Fluorescence Immunoassays; Chemiluminescence Immunoassays; Immunofixation and Immunoblotting; Clinical Indications for Electrophoresis and Immunofixation; SECTION B: MOLECULAR BIOLOGY METHODS; Introduction to Molecular Methodology; Choosing Appropriate Methodologies in the Clinical Environment: Immunological Techniques versus Molecular Methods; Keys to Successful In Situ PCR; SECTION C: IMMUNOGLOBULIN METHODS; Introduction; Immunoglobulin Quantitation; Immunoglobulin Genes; Immunochemical Characterization of Immunoglobulins; SECTION D: COMPLEMENT, IMMUNE COMPLEXES, AND CRYOGLOBULIN; Introduction; Complement Tests; Complement Activation; Complement Receptors; Genetic Typing of the Complement System; Tests for Circulating Immune Complexes and Autoantibodies to C 1 q; Cryoglobulins; SECTION E: IMMUNE CELL PHENOTYPING AND FLOW CYTOMETRIC ANALYSIS; Introduction; Immunophenotyping by Flow Cytometry; Functional Assays by Flow Cytometry; Flow Cytometric Analysis of DNA Content in Solid Tumors; Emerging Clinical Applications of Flow Cytometry: Microbiology and Parasitology; SECTION F: IMMUNE CELL ASSAYS; Introduction; Delayed Hypersensitivity Skin Testing; Cryopreservation of Peripheral Blood Mononuclear Cells; T-Lymphocyte Activation; Cytolytic Cell Functions; Methods for Identification of the T-Cell Antigen Receptor; Lymphocyte Proliferation; Phagocytic Cell Functions I: Oxidation and Chemotaxis; Phagocytic Cell Functions II: Adhesion and Phagocytosis; Methods for Analysis of Apoptosis by Flow Cytometry; SECTION G: IMMUNE CELL PRODUCTS; Introduction; Cytokines and Immune Cell Products; Development and Use of Cytokine and Growth Factor Potency Standards; Measuring Cell Adhesion Molecules; SECTION H: IMMUNOHISTOLOGY AND IMMUNOPATHOLOGY; Introduction; Immunohistochemistry: Principles and Practice; Immunohistochemistry in the Diagnosis of Solid Tumors; Immunohistochemistry in the Diagnosis of Lymphomas; Prognostic Markers in Immunohistochemistry; In Situ Hybridization as an Adjunct Method with Immunohistochemistry; Immunofluorecence Methods for Diagnosis of Renal and Skin Diseases; Immunoelectron Microscopy in Diagnostic Pathology; PART II: IMMUNOLOGIC DIAGNOSIS AND MONITORING OF DISEASE; SECTION I: INFECTIOUS DISEASES CAUSED BY BACTERIA, MYCOPLASMAS, CHLAMYDIAE, AND RICKETTSIAE; Introduction; Immune Response to Streptococcal Antigens: Diagnostic Methods; Haemophilus influenzae Type b, Neisseria meningitidis, Streptococcis pneumoniae, and Corynebacterium diptheriae Vaccines; Clostridium tetani: Immune Response and Diagnostic Methods; Immunologic Methods for Diagnosis of Infections by Gram-Negative Cocci; Immunologic Methods for the Diagnosis of Infections Caused by Diarrheagenic Members of the Families Enterobacteriaceae and Vibrionaceae; Serodiagnosis of Helicobacter pylori Infection; Detection of Antibodies to Legionella spp.; Immunologic Methods for Diagnosis of Spirochetal Diseases; Lyme Disease: Serodiagnosis of Borrelia burgdorferi Sensu Lato Infection; Immunological Procedures for Diagnosis of Tuberculosis and Leprosy; Nocardiae and Agents of Actinomycosis; Mycoplasma Infection: Immunologic and Molecular Biologic Diagnostic Techniques; Chlamydiae; Immunoserology of Rickettsiae; SECTION J: MYCOTIC AND PARASITIC DISEASES; Introduction to Clinical Immunomycology and Clinical Immunoparasitology; Clinical Immunoparasitology; Clinical Immunomycology; SECTION K: VIRAL DISEASES; Introduction; Rapid Viral Diagnosis; Antibody-Enhanced Detection of Viruses in Cell Cultures; Herpes Simplex Virus; Varicella-Zoster Virus; Epstein-Barr Virus; Cytomegalovirus; Human Herpesviruses 6 and 7; Papovaviruses; Adenoviruses; Parvovirus B 1 9; Influenza Viruses; Respiratory Syncytial Virus and Parainfluenza Viruses; Measles and Mumps; Rubella Virus; Enteroviruses; Hepatitis Viruses; Enzyme Immunoassays for Detection of Rotavirus Antigen and Antibody; Arboviruses; Hantaviruses; Marburg Virus, Ebola Virus and the Arenaviruses; Rabies Virus; SECTION L: HUMAN IMMUNODEFICIENCY VIRUS; Introduction; Immunologic Evaluation of Patients with Human Immunodeficiency Virus Infection; Quantitation of Viremia in Human Immunodeficiency Virus Infection; Isolation and Detection of Human Immunodefiency Virus; Principles and Procedures of Human Immunodeficiency Virus Serodiagnosis; Sequence Analysis of Human Immunodeficiency Virus Type 1 Haplotypes; SECTION M: IMMUNODEFICIENCY DISEASES; Introduction; Genetics and Inherited Immunodeficiency Diseases and Diagnostic Techniques; Combined B- and T-Cell Deficiencies; Investigation of Signal Transduction Defects; Primary Antibody Deficiencies in Children and Adults; Inherited and Acquired C 1 -Inhibitor Deficiency; Genetically Determined Deficiencies of the Complement System: C 1 , C 4, C 2, and C 3; Alternative Pathway and Late Complement Component Deficiencies; Neutropenia and Neutrophil Defects; SECTION N: ALLERGIC DISEASES; Introduction; Quantitation and Standardization of Allergens; In Vivo Diagnostic Allergy Testing Methods; Immunological Tests for Diagnosis and Management of Human Allergic Disease: Total and Allergen-Specific IgE and Allergen-Specific IgG; Tests for Immunological Reactions to Drugs and Occupational Allergens; Assay Methods for the Measurement of Mediators and Markers of Allergic Inflammation; Immunological Tests for Evaluation of Hypersensitivity Pneumonitis and Allergic Bronchopulmonary Aspergillosis; SECTION O: SYSTEMIC AUTOIMMUNE DISEASES; Introduction; Immunofluorescent Antinuclear Antibody Tests; Detection of Autoantibodies to Ribonucleoprotein Part icles by Immunoblotting; Enzyme-Linked Immunosorbent Assays for Antibodies to Native DNA, Histones, and (H 2A-H 2B)-DNA; Rheumatoid Factors; Antiphospholipid Antibodies; Antineutrophil Cytoplasmic Antibodies; Autoantibodies to Complement Components; SECTION P: ORGAN-LOCALIZED AUTOIMMUNE DISEASES; Introduction; Endocrinopathies; Detection of Autoantibodies in Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome; Detection of Antimitochondrial Autoantibodies in Primary Biliary Cirrhosis and Liver-Kidney Microsomal Antibodies in Autoimmune Hepatitis; Skin Diseases; Cardiovascular Diseases; Kidney and Lung Disease Mediated by Glomerular Basement Membrane Antibodies: Detection by Western Blot Analysis; Human Spermatozoa Antibodies: Detection and Clinical Significance; Autoimmune Hemolytic Anemias; Autoimmune Thrombocytopenia; SECTION Q: CANCER; Introduction; Human Tumor Antigens Recognized by T Lymphocytes; Cancer Vaccines; Cancer Genes and Early Cancer Detection; Malignancies of the Lymphoid and Histiocytic Systems; Monitoring of Immunologic Therapies; SECTION R: TRANSPLANTATION IMMUNOLOGY AND IMMUNOGENETICS; Introduction: Genes in the Human Major Histocompatibility Complex Relevant to Immune Regulation and Transplantation and Other Clinical Applications; Histocompatibility Testing by Immunologic Methods: Cellular Assays; Histocompatability Testing by Immunologic Methods: Humoral Assays; HLA Typing by Molecular Methods; Pre-Transplant Histocompatibility Assessment for Solid Organ Transplantation; Immunological Characterization of Solid Organ Graft Recipients; Histocompatibility Assessment in Bone Marrow Transplantation; Statistical Analysis and Applications of HLA Population Data; Principles and Applications of Genetic Identification; PART III: ADMINISTRATION; SECTION S: LABORATORY MANAGEMENT; Introduction; Establishment and Verification of Reference Values; Standardization of Immunoassay Methodologies; Quality Assurance; Planning Statistical Quality Control Procedures; Interlaboratory Proficiency Testing in Laboratory Immunology; Clinical Significance and Cost-Effectiveness of Clinical Immunology Testing; Laboratory Safety

Erscheint lt. Verlag 3.6.1997
Verlagsort Washington DC
Sprache englisch
Gewicht 3131 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Laboratoriumsmedizin
Studium Querschnittsbereiche Infektiologie / Immunologie
ISBN-10 1-55581-118-3 / 1555811183
ISBN-13 978-1-55581-118-1 / 9781555811181
Zustand Neuware
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