Human Embryonic Stem Cells

Arlene Chiu, Mahendra S. Rao (Herausgeber)

Buch | Hardcover

461 Seiten

2003
Humana Press Inc. (Verlag)
978-1-58829-311-4 (ISBN)

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A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Part I. Policy

Ethical Issues Associated with Pluripotent Stem Cells
Steve Usdin

A Researcher's Guide to Federally Funded Human Embryonic Stem Cell Research in the United States
Gregory J. Downing

Intellectual Property of Human Pluripotent Stem Cells
Mark L. Rohrbaugh

Part II. Types of Pluripotent Cells

Embryonal Carcinoma Cells: The Malignant Counterparts of ES and EG Cells
Jonathan S. Draper, Harry Moore, and Peter W. Andrews

Human Pluripotent Cells from Bone Marrow
Felipe Prosper and Catherine M. Verfaillie

Protocols for the Isolation and Maintenance of Human Embryonic Stem Cells
Melissa K. Carpenter, Chunhui Xu, Christine A. Daigh, Jessica E. Antosiewicz, and James A. Thomson

Subcloning and Alternative Methods for the Derivation and Culture of Human Embryonic Stem Cells
Michal Amit, Hanna Segev, Dorit Manor, and Joseph Itskovitz-Eldor

Part III. Differentiation

Differentiation of Neuroepithelia from Human Embryonic Stem Cells
Su-Chun Zhang

Pancreatic Differentiation of Pluripotent Stem Cells
Nadya Lumelsky

Human Embryonic Stem Cell-Derived Cardiomyocytes: Derivation and Characterization
Chunhui Xu and Melissa K. Carpenter

Vascular Lineage Differentiation from Human Embryonic Stem Cells
Sharon Gerecht Nir and Joseph Itskovitz-Eldor

Hematopoietic Progenitors Derived from Human Embryonic Stem Cells
Dan S. Kaufman

Part IV. Therapeutics

Human Embryonic vs Adult Stem Cells for Transplantation Therapies
Calvin B. Harley and Mahendra S. Rao

Genetic Manipulation of Human Embryonic Stem Cells
Micha Drukker and Nissim Benvenisty

Human Therapeutic Cloning
Jose B. Cibelli

Therapeutic Uses of Embryonic Stem Cells
Alexander Kamb, Mani Ramaswami, and Mahendra S. Rao

Human Embryonic Stem Cells and the Food and Drug Administration: Assuring the Safety of Novel Cellular Therapies
Donald W. Fink, Jr.

Studies of a Human Neuron-Like Cell Line in Stroke and Spinal Cord Injury: Preclinical and Clinical Perspectives
Paul J. Reier, John Q. Trojanowski, Virginia M-Y. Lee, and Margaret J. Velardo

Appendix I: Cell Lines and Companies Involved with Human Embryonic Stem Cell Research

Appendix II: Useful Websites

"This is an excellent compendium about human stem cells..." -Biologist

Erscheint lt. Verlag	1.8.2003
Zusatzinfo	49 Illustrations, black and white; XVIII, 461 p. 49 illus.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Gynäkologie / Geburtshilfe
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Biologie ► Zellbiologie
ISBN-10	1-58829-311-4 / 1588293114
ISBN-13	978-1-58829-311-4 / 9781588293114
Zustand	Neuware