Handbook of Hematologic Malignancies (eBook)

David A. Sallman, Ateefa Chaudhury, Ling Zhang (Herausgeber)

Johnny Nguyen (Autor)

eBook Download: PDF

2020 | 2. Auflage
500 Seiten
Springer Publishing Company (Verlag)
978-0-8261-4977-0 (ISBN)

Infos

This revised and updated second edition of Handbook of Hematologic Malignancies continues to be an essential and "e;go-to"e; resource for the busy hematologist, hematologic oncologist, hematopathologist, oncology advanced practice provider, oncology nurse, and trainee. Concisely organized, each chapter provides the most current, need-to-know points of diagnosis, prognosis, therapeutic management, and clinical trial opportunities for each hematological malignancy. Chapters are complete with richly illustrated figures to highlight the hematopathologic characteristics of diseases in addition to helpful tables on differential diagnosis, prognostic scoring systems, molecular profiles, and therapeutic options. A new case-based chapter concludes the handbook with clinical cases designed to test a clinician's knowledge of pathologic diagnosis and clinical presentation of diseases covered in the book. With over twenty new FDA-approved indications since publication of the first edition, including breakthroughs with CAR-T therapy, and other evidence-based treatment options for patients with hematologic disease, this book serves as quick reference to practice changing information on challenging diagnostic dilemmas, frontline and refractory treatment scenarios, and more.The subspecialty field of hematologic oncology is ever-changing and expanding with available treatment options and this second edition keeps the busy clinician abreast of recent findings and their impact on evidence-based treatment and management. Written by experienced clinicians at the world-renowned Moffitt Cancer Center in Tampa, Florida, as well as contributions from leading academicians, hematologists, and oncologists throughout the country, this unique handbook is packed with authoritative knowledge and clinical insight into all known hematologic cancers.Key Features:Includes seven new chapters covering CAR-T and novel therapeutic options including CD19 CAR-T therapy, novel cellular therapies, cytokine release syndrome, cancer associated thrombosis, and moreComprises compact and updated disease-site chapters describing new standards of care and management considerations in bullet point format with key referencesHighlights important diagnostic tools that assist with conducting key differential diagnoses and unveiling answers to diagnostic dilemmasProvides updates of potential practice-changing clinical trials and paradigm shifting treatment considerations in each disease-based chapter

Inhalt

Contributors

Preface

PART I: INTRODUCTION AND OVERVIEW

Chapter 1. Normal Hematopoiesis and Diagnosis Algorithms for Cytopenias and Cytoses

Chapter 2. Familial/Inherited Mutations and Risks of Hematologic Malignancies

Chapter 3. Hematopathology Diagnostic Techniques and Assays

Chapter 4. Minimal Residual Disease Assays

PART II: MYELOPROLIFERATIVE NEOPLASMS

Chapter 5. Polycythemia Vera

Chapter 6. Essential Thrombocythemia

Chapter 7. Primary Myelofibrosis

Chapter 8. Chronic Myelogenous Leukemia

Chapter 9. Chronic Neutrophilic Leukemia

Chapter 10. Systemic Mastocytosis

Chapter 11. PDGFRA/PDGFRB/FGFR1 Myeloid Neoplasms

PART III: MYELODYSPLASTIC AND BONE MARROW FAILURE SYNDROMES

Chapter 12. Myelodysplastic Syndromes

Chapter 13. Aplastic Anemia

Chapter 14. Paroxysmal Nocturnal Hemoglobinuria

PART IV: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASMS

Chapter 15. Myelodysplastic/Myeloproliferative Overlap Syndromes

Chapter 16. Chronic Myelomonocytic Leukemia

PART V: ACUTE MYELOID LEUKEMIA AND RELATED SYNDROMES

Chapter 17. Acute Myeloid Leukemia

Chapter 18. Secondary AML and AML With Myelodysplasia-Related Changes

Chapter 19. Acute Promyelocytic Leukemia

Chapter 20. Blastic Plasmacytoid Dendritic Cell Neoplasm

PART VI: ACUTE LYMPHOID LEUKEMIA

Chapter 21. B-Lymphoblastic Leukemia/Lymphoma

Chapter 22. BCR-ABL1+ B-Lymphoblastic Leukemia

Chapter 23. T-Lymphoblastic Lymphoma/Leukemia  

PART VII: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE

Chapter 24. Acute Leukemia of Ambiguous Lineage

PART VIII: MATURE T- AND NK-CELL LEUKEMIA

Chapter 25. T-Cell Prolymphocytic Leukemia

Chapter 26. T-Cell Large Granular Lymphocytic Leukemia

Chapter 27. Aggressive Natural Killer Cell Leukemia

PART IX: PLASMA CELL DISORDERS

Chapter 28. Monoclonal Gammopathy of Unknown Significance, Smoldering Myeloma, and Plasmacytomas

Chapter 29. Multiple Myeloma

Chapter 30. Waldenström’s Macroglobulinemia

Chapter 31. Immunoglobulin Light Chain Amyloidosis

PART X: HODGKIN LYMPHOMA

Chapter 32. Hodgkin Lymphoma

PART XI: NON-HODGKIN LYMPHOMA

Chapter 33. Non-Hodgkin Lymphoma Classification and Diagnostic Evaluation

PART XII: MATURE B-CELL LYMPHOMA

VERY AGGRESSIVE

Chapter 34. Burkitt Lymphoma

AGGRESSIVE

Chapter 35. Diffuse Large B-Cell Lymphoma

Chapter 36. Double Hit Lymphoma

Chapter 37. Mantle Cell Lymphoma

Chapter 38. Primary Mediastinal Large B-Cell Lymphoma

Chapter 39. Primary Central Nervous System Lymphoma

Chapter 40. HIV-Related Lymphomas

INDOLENT

Chapter 41. Follicular Lymphoma

Chapter 42. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chapter 43. Hairy Cell Leukemia

Chapter 44. Marginal Zone Lymphoma

Chapter 45. Mucosa-Associated Lymphoid Tissue Lymphoma

PART XIII: MATURE T/NK-CELL LYMPHOMA

Chapter 46. Adult T-Cell Leukemia/Lymphoma

Chapter 47. Anaplastic Large Cell Lymphoma, ALK Positive

Chapter 48. Extranodal Natural Killer/T-Cell Lymphoma

Chapter 49. Mycosis Fungoides

Chapter 50. Hepatosplenic T-Cell Lymphoma

PART XIV: HISTIOCYTIC/DENDRITIC CELL NEOPLASMS

Chapter 51. Histiocytic Sarcoma, Langerhans Cell Histiocytosis, Erdheim-Chester Disease, and Rosai-Dorfman Disease

Chapter 52. Hemophagocytic Lymphohistiocytosis

PART XV: BONE MARROW TRANSPLANTATION

Chapter 53. Autologous Bone Marrow Transplantation

Chapter 54. Allogeneic Bone Marrow Transplantation

PART XVI: NEW CELLULAR IMMUNOTHERAPY

Chapter 55. CAR-T and Novel Cellular Therapeutic Options in Hematologic Malignancies

Chapter 56. CD19 CAR-T Therapy

Chapter 57. Cytokine Release Syndrome

PART XVII: EMERGENCIES IN HEMATOLOGY

Chapter 58. Cancer Associated Thrombosis

Chapter 59. Tumor Lysis Syndrome

Chapter 60. Thrombotic Microangiopathy

Chapter 61. Therapeutic Apheresis Indications

PART XVIII: NEW CLINICAL CASES IN MALIGNANT HEMATOLOGY

Chapter 62. Challenging Case Vignettes with Follow-Up Questions

Appendix: Pathology Supplement

Produkt-Details

• Erscheint lt. Verlag: 15.1.2021
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Schlagworte: cellular immunotherapy,clinical cases,differential diagnoses,hematologic malignancies,prognosis,therapeutic management
• ISBN-10: 0-8261-4977-4 / 0826149774
• ISBN-13: 978-0-8261-4977-0 / 9780826149770