Molecular Nuclear Medicine

The Challenge of Genomics and Proteomics to Clinical Practice

L.E. Feinendegen, W.W. Shreeve, W.C. Eckelman, Y.-W. Bahk, H.N. Jr. Wagner (Herausgeber)

Buch | Hardcover

XX, 795 Seiten

2003
Springer Berlin (Verlag)
978-3-540-00132-4 (ISBN)

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Nuclear Medicine techniques have advanced to such a degree that biochemical transparency of the human body has reached the doorstep of medical application. The book gives background, techniques and examples in an interdisciplinary approach to quantify biochemical reactions in vivo by regional imaging and in vitro analyses. The goal is to assess in vivo biochemical homeostatic circuits under control by genes and protein interactions. It becomes apparent how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships operating in vivo and thus can help eventually to bring functional genomics and proteomics to clinical medicine.

Over six hundred fifty scientific publications, especially on cell biology, molecular nuclear medicine for in vivo analysis of biochemical reactions, cell responses to low doses of ionizing radiation and to strong static magnetic fields in single- and multi- cellular systems. - Member of numerous national and international advisory groups, committees, boards. Member, Northrhine-Westfalian Academy of Sciences, Germany. Vice-president, Committee for the Annual Meetings of Nobel Prize Winners in Lindau, Germany. Numerous scientific awards and prices.

From the contents: Feinendegen et al.: Measurements of Biochemical Reactions in Vivo; Passarge: The Human Genome and Disease; Kley et al: Functional Genomics and Proteomics; Fischer: How Proteins Speak with one Another in Cell Signaling; Eckelman: Labeled Agents as Tracers and Carriers: Theory and Practice; Sharp et al: Instrumentation for Measuring Metabolism; Gjedde: Modelling Metabolite and Tracer Kinetics; Bassingthwaighte: Compound Delivery and Local Blood Flows; Dawson et al: Endothelium and Compound Transfer; Rosenthall: Coagulation and Peripheral Vascular Disease; Rennen et al: Molecular Imaging of Infection and Inflammation; Shreeve et al: Element of Metabolism and Body Composition; Pierson/Shreeve: The Biology of Aging and Related Nuclear Medicine Studies; Shreeve: In Vitro Indicators of Metabolism of Natural Compounds; Konishi et al: Endocrinology; Epstein/Bergmann: Non-invasive Assessment of Inherited Cardiac Disease; Egert/Schwaiger: Molecular Background of FDG Uptake in the Ischemic Heart; Volkow et al: Imaging Studies in Substance Abuse; Kuwert: Imaging of Cerebral Metabolism in Huntington's Disease; Fowler et al: Monoamine Oxidase: Radiotracer Development and Human Studies.

Sprache	englisch
Maße	193 x 270 mm
Gewicht	2440 g
Einbandart	gebunden
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
Schlagworte	Hardcover, Softcover / Medizin/Klinische Fächer • HC/Medizin/Klinische Fächer • Nuklearmedizin
ISBN-10	3-540-00132-8 / 3540001328
ISBN-13	978-3-540-00132-4 / 9783540001324
Zustand	Neuware