Locoregional Radionuclide Cancer Therapy
Springer International Publishing (Verlag)
978-3-030-56266-3 (ISBN)
Throughout the chapters, the clinical and scientific bases of use of radionculides in humans are explored. Mathematical models of radiation dosimetry of locoregional radionculdies effects on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals and the human, clinical ramifications that come of these animal models are considered in depth. Unlike systemic administration of radionuclides, locoregional injections in animal tumor models indeed provide invaluable insights to clinical studies. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed.
This is an ideal guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for the design and use of locoregional radionuclide cancer therapies.
Franklin C. L. Wong University of Texas MD Anderson Cancer Center Houston, TX USA
Preface
Acknowledgements
Chapter 1: Human Cancer- Epidemiology, Hallmarks, and Defense Strategies
Chapter 2: Cancer Treatment Modalities Systemic and Loco regional Approaches: Challenges and Opportunities of multidisciplinary approaches
Chapter 3: Cancer Radiotherapy: General Considerations and Human Radiobiology
Chapter 4: Radionuclide Cancer Therapy- Unsealed Alpha, Beta and Gamma Emitters
Chapter 5: Locoregional Therapy - Cancer Interventions with and without Radionuclides
Chapter 6: Radiation Dosimetry Considerations of Locoregional Radionuclide Cancer Therapy
Chapter 7: Voxel-based Targeted Radionuclide Therapy Dosimetry
Chapter 8: Locoregional Unsealed Radionuclide Cancer Therapy - Experimental Findings
Chapter 9: Animal Cancer Therapy Models - Ready Translation to Humans
Chapter 10: An Overview of Regulations of Radiopharmaceuticals
Chapter 11: Locoregional Radionuclide Cancer Therapy (LRCT) Using Sealed & Unsealed Radionuclides
| Erscheinungsdatum | 05.01.2021 |
|---|---|
| Zusatzinfo | XII, 268 p. 76 illus., 56 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Nuklearmedizin |
| Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie | |
| Schlagworte | Cancer Therapy • Imaging algorithms • Leptomeningeal metastasis • Locoregional • locoregional radionuclide cancer therapies • LRCT • Radionuclide Therapy |
| ISBN-10 | 3-030-56266-2 / 3030562662 |
| ISBN-13 | 978-3-030-56266-3 / 9783030562663 |
| Zustand | Neuware |
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