Chemical and Structural Approaches to Rational Drug Design
CRC Press (Verlag)
978-0-367-44931-5 (ISBN)
This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. The book features contributors from a variety of fields, new techniques, previously unpublished data, and extensive reference lists.
Weiner, David B. | Williams, William V.
Section I: Chemical Approaches to Rational Drug Design 1. Design, Synthesis and Antitumor Activity of an Inhibitor of Ribonucleotide Reductase 2. The Development of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors 3. The Development of Potent Angiotensin II Receptor Antagonists Using a Novel Peptide Pharmacophore Model 4. Endothelin Structure and Development of Receptor Antagonists 5. Molecular Targeting Chemistry in Rational Drug Design Section II: Structural Approaches to Rational Drug Design 6. The Role of X-Ray Crystallography in Structure-Based Rational Drug Design 7. Biocomputational Approaches to Protein-Based Drug Design 8. Architecture and Design of Zinc Protein-Ligand Complexes 9. Design of Immunomodulatory Peptides Based on Active Site Structures
| Erscheinungsdatum | 01.07.2020 |
|---|---|
| Reihe/Serie | Handbooks in Pharmacology and Toxicology |
| Verlagsort | London |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Gewicht | 453 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Technik | |
| ISBN-10 | 0-367-44931-5 / 0367449315 |
| ISBN-13 | 978-0-367-44931-5 / 9780367449315 |
| Zustand | Neuware |
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