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Environmental Endocrinology and Endocrine Disruptors -

Environmental Endocrinology and Endocrine Disruptors

Endocrine and Endocrine-targeted Actions and Related Human Diseases
Buch | Hardcover
XXII, 520 Seiten
2023 | 1st ed. 2023
Springer International Publishing (Verlag)
978-3-030-39043-3 (ISBN)
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This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to 'living editions' that are constantly updated using a dynamic peer-review publishing process.

Prof. Rosario Pivonello is Associate Professor of Endocrinology at "Federico II" University of Naples, Italy. In 2003, he received a PhD in Neuropsychopharmacology and Toxicology at "Federico II" University, and in 2005 a PhD in Internal Medicine (Basic and Clinical Endocrinology) at Erasmus University, in Rotterdam, The Netherlands, focusing his research on the role of dopaminergic system in pituitary and adrenal tumors. His major clinical interest and scientific research production include pituitary and adrenal diseases, with a focus on Cushing's syndrome, for which he is recognized as expert by the scientific community. He is principal investigator of international multicenter studies on Cushing's syndrome, acromegaly and adrenal diseases, and of national research projects in endocrinology, funded by the Italian Ministry of University and Research (MIUR) and Italian Ministry of Health (MoH). In the last decade, his clinical and research interests include the study of andrology and sexual medicine. In 2011 he pursued a Master in Andrology and Sexual Medicine at University of Florence, Italy and in 2016 a Master in Andrology and Seminology at "La Sapienza" University of Rome, Italy. He is Director of the "FERTISEXCARES", Centre of Andrology and Medicine of Male and Female Reproduction and Sexuality (Excellence Centre of the Italian Society of Andrology and Sexual Medicine - SIAMS) at University Hospital "Federico II", and head of the homonym Intra-departmental program, and head of the Andrology program within the UNESCO Chair "Health Education an Sustainable Development", "Federico II" University (Chair coordinator Prof. Annamaria Colao). His most recent clinical and research activity in the field of reproduction and fertility includes a national multicenter observational study (GONADIS) on gonadal status and reproductive and sexual function in patients of both sexes with pituitary and adrenal disorders, of which he is the coordinator, and regional research projects in andrology, funded by Campania Regional Government, of which he is the principal investigator. He got several national and international Committee Membership and Editorship. Presently, he is member of the Executive Committee of the European Neuroendocrine Association (ENEA) (2016 to date). He is coordinator of the Scientific Committee (2018 to date) and has been coordinator of the "Drugs" Committee (2017-2019), member of Scientific Committee (2010-2012), and member of Executive Committee (2012-2016) in the Italian Society of Andrology and Sexual Medicine (SIAMS). In the Italian Society of Endocrinology (SIE), he is member of the Scientific Committee (2017 to date) and coordinator of the SIE Club "Endocrinology and Metabolism of Sport and Physical Exercise" (2018 to date). He is Associate Editor for Frontiers in Endocrinology, section of "Pituitary Endocrinology" (2017 to date), and Editorial Board Member for the International Journal of Molecular Sciences, section "Molecular Endocrinology and Metabolism" (2019 to date). Moreover, he is member of the Register of Expert Peer Reviewers for Italian Scientific Evaluation (MIUR-REPRISE) (2015 to date) and expert peer reviewer of Deutsche Forschungsgemeinschaft (DFG) (2016 to date), German Research Foundation. Among the academic achievement, he is member of the Committee of Lecturers for the PhD in "La Sapienza" University and faculty member of PhD courses at "Federico II" University. He is author of more than 330 scientific publications . His h-index is 61; Citations: 11468 (Scopus) https://www.scopus.com/authid/detail.uri?authorId=7005921464. He is ranked in the Italian Top Scientist List:http://www.topitalianscientists.org/top_italian_scientists_VIA Academy.aspx?Cerca=Rosario%20Pivonello

Environmental endocrinology: basic concepts.- Environmental impact on the hypothalamus-pituitary axis.- Environmental impact on the hypothalamus-pituitary-thyroid axis.- Environmental impact on  the hypothalamus-pituitary-adrenal axis.- Environmental impact on  the hypothalamus-pituitary-ovary axis.- Environmental impact on female fertility and pregnancy.- The role of the environment in female reproductive disorders.- Environmental impact on the  hypothalamus-pituitary-testis axis.- Environmental impact on semen quality and male fertility.- The role of the environment in testicular dysgenesis syndrome.- Environmental impact on sexual response.- Environmental impact on bone health.- Environmental impact on the immune system.- Environmental impact on metabolism.- The role of the environment in neuroendocrine tumors.- The role of the environment in endocrine cancers.- The role of the environmentin hormone-related cancers.

Erscheinungsdatum
Reihe/Serie Endocrinology
Zusatzinfo XXII, 520 p. 40 illus., 2 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 971 g
Themenwelt Medizinische Fachgebiete Innere Medizin Endokrinologie
Schlagworte Cancer • endocrine axes • environmental chemicals • Hormone • Human health • hypogonadism • Infertility
ISBN-10 3-030-39043-8 / 3030390438
ISBN-13 978-3-030-39043-3 / 9783030390433
Zustand Neuware
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