Gene Mutations

Causes and Effects

Buch | Softcover

136 Seiten

2020
Nova Science Publishers Inc (Verlag)
978-1-5361-6984-3 (ISBN)

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A gene is a DNA sequence that can be transcribed into an RNA molecule and transferred to offspring organisms. Changes in DNA sequences that determine the structure and function of a gene are called mutations. Gene Mutations: Causes and Effects opens by exploring the physical, chemical, and biological agents that cause mutations interact with DNA, leading to genetic instability. Recent advances in next-generation sequencing have led to the discovery of new causative genes or those mutations. The authors describe the phenotypes and gene mutations, discussing genotype-phenotype correlations compared with previous reports. Lastly, one study analyses all conflicting data concerning the amplification of the ESR1 gene, particularly its ambiguous prevalence in both untreated tumors and tumors either responsive or unresponsive to antiestrogen therapy.

PrefaceTypes of Gene Mutations and Their MechanismsGene Mutations of Hereditary Motor Neuron DiseasesESR1 Gene Amplification in Breast Cancers is an Effort for DNA Stabilization and a Consequential Tumor ResponseIndex.

Erscheinungsdatum	18.02.2020
Verlagsort	New York
Sprache	englisch
Maße	152 x 229 mm
Gewicht	198 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
ISBN-10	1-5361-6984-6 / 1536169846
ISBN-13	978-1-5361-6984-3 / 9781536169843
Zustand	Neuware