Inflammatory Bowel Diseases
Churchill Livingstone (Verlag)
978-0-443-03819-8 (ISBN)
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Though the aetiology and pathogenesis of inflammatory bowel diseases (ulcerative colitis, Crohn's disease) remain obscure, substantial progress has been made in the understanding of these challenging disorders since the first edition of "Inflammatory Bowel Diseases" in 1983. Scientific advances include characterization of the nature of the intestinal inflammatory reaction, delineation of the varied immunological events, and the application of numerous basic scientific disciplines (including biochemistry, pharmacology, cell biology, gastrointestinal neuroendocrinology, immunology, genetics, and molecular biology) to the investigation of inflammatory bowel diseases. In addition to careful clinical observation, clinical progress includes expanding epidemiological and familial studies, documentation of the clinical complexities of inflammatory bowel disease, assessment of the cancer risk, and such therapeutic advances as improved nutritional support, the use of elemental diets in Crohn's disease, 5-aminosalicylic acid compounds in ulcerative colitis, immunosuppressive and other anti-inflammatory medications.
In the surgery of inflammatory bowel diseases, total colectomy and ileoanal anastomosis is increasingly preferred for many patients with ulcerative colitis requiring operation; while in Crohn's disease the advantages and the limitations of surgery have been defined more clearly with particular emphasis on preserving as much small bowel as possible. The second edition of "Inflammatory Bowel Diseases" incorporates all of these developments and more, in a systematic and thorough account of inflammatory bowel diseases.
Part 1 History of genetics and epidemiology: historical review, C.Hawkins; genetics of inflammatory bowel disease, R.B.McConnell; epidemiology of inflammatory bowel disease, M.J.S.Langman. Part 2 Pathophysiology: pathophysiology of small intestinal function and the effect of Crohn's disease, V.S.Chadwick and M.Camilleri; absorption of fluids and electrolytes by the colon - relevance to inflammatory bowel disease, C.Steadman and S.F.Phillips; disturbances of intestinal motor activity in inflammatory bowel disease, S.S.C.Rao and N.W.Read; anorectal function, M.R.B.Keighley and M.Pinho; ileostomy function, G.L.Hill; hepatic function, bile excretion and gallbladder function in Crohn's disease, P.Rutgeerts and G.Vantrappen; infection and surgery, R.G.Tudor and M.R.B.Keighley. Part 3 Aetiology: one disease or two, H.J.F.Hodgson; immunology of ulcerative colitis and Crohn's disease, D.P.Jewell and J.A.Snook; the aetiology of inflammatory bowel disease - the role of infectious agents, W.R.Thayer; dietary factors in the aetiology of inflammatory bowel disease, K.W.Heaton; mucus and inflammatory bowel diseases, J.M.Rhodes; animal models, J.M.Rhodes. Part 4 Diagnosis: differential diagnosis, ulcerative colitis, Crohn's disease and other disorders, including diverticular disease, P.Riis; laboratory investigations and disease activity in inflammatory bowel disease, J.W.Singleton; ulcerative colitis - radiology, K.Evers and I.Laufer; radiology - Crohn's disease, J.R.Lee; histopathology of ulcerative colitis, J.B.Dixon and R.H.Riddell; histopathology of Crohn's disease, H.Thompson; endoscopy in inflammatory bowel disease, R.H.Hunt. Part 5 Clinical presentation - natural history and prognosis: ulcerative colitis, V.Binder; proctitis, A.Allan; Crohn's disease of the small intestine, H.A.Andrews and R.N.Allan; Crohn's disease of the large intestine, R.G.Farmer; oral, oesophageal and gastro-duodenal Crohn's disease, I.T.Weterman; perianal lesions in Crohn's disease. Part 6 Medical treatment: sulphasalazine and aminosalicylates in treatment, M.J.Dew; corticosteroid and immunosuppressive drugs,m J.E.Lenanrd-Jones; medical management of ulcerative colitis, J.M.Rhodes; medical management of Crohn's disease, R.N.Allan; nutritional therapy of inflammatory bowel diseases, J.B.Mason and I.H.Rosenberg. Part 7 Surgical treatment: ulcerative colitis - indications for emergency and elective surgery, N.Williams.
Erscheint lt. Verlag | 17.9.1990 |
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Vorwort | J.B. Kirsner |
Zusatzinfo | 104 tables, 78 line drawings, 96 half-tones |
Verlagsort | London |
Sprache | englisch |
Maße | 305 x 52 mm |
Gewicht | 2002 g |
Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Gastroenterologie |
ISBN-10 | 0-443-03819-8 / 0443038198 |
ISBN-13 | 978-0-443-03819-8 / 9780443038198 |
Zustand | Neuware |
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