Behavioral Study of Agonist-Evoked Activation of Transient Receptor Potential Channels
Seiten
2019
Nova Science Publishers Inc (Verlag)
978-1-5361-6501-2 (ISBN)
Nova Science Publishers Inc (Verlag)
978-1-5361-6501-2 (ISBN)
This book provides an original account of behavioral aspects with important ramifications for the study of transient receptor potential (TRP) channels functioning. It explains, in terms of specified somato-sensory mechanisms and systems, how TRP channels work. Through exploration of animal models by testing paw withdrawal reflexes to thermal and mechanical stimuli, it is shown that TRP channels are promising targets for the development of a new group of analgesic drugs at the periphery and central levels and opportunities for therapeutic intervention.
Head, Pain Research Lab, Chief Research Scientist, Ivane Beritashvili Experimental Biomedicine Center, Tbilisi, Georgia
PrefaceAbbreviationsIntroductionPhylogeny of TRP ChannelsStructural-Functional Characteristics of TRP ChannelsA Short Review of TRP SuperfamilyThermo-TRP ChannelsTRP Channels in Physiological Nociception and PainTRP Channels as Therapeutic and Analgesic TargetsTRP Channels and NSAIDsConcluding Remarks and PerspectivesReferencesIndex.
| Erscheinungsdatum | 16.08.2019 |
|---|---|
| Sprache | englisch |
| Gewicht | 284 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Schmerztherapie |
| ISBN-10 | 1-5361-6501-8 / 1536165018 |
| ISBN-13 | 978-1-5361-6501-2 / 9781536165012 |
| Zustand | Neuware |
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