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Human Growth Hormone Pharmacology -

Human Growth Hormone Pharmacology

Basic and Clinical Aspects
Buch | Hardcover
192 Seiten
1995
Crc Press Inc (Verlag)
978-0-8493-8384-7 (ISBN)
CHF 119,95 inkl. MwSt
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Addresses a wide range of basic and clinical issues in the physiology and pharmacology of growth hormone. This book presents the factors contributing to GH gene expression, the functional relationships of the GH receptor, molecular biological analysis of the GH-GH receptor complex and proceeds to describe the insulin-like growth factor axis.
This book addresses a wide range of basic and clinical issues in the physiology and pharmacology of growth hormone. The volume is organized like a textbook. It begins with factors contributing to GH gene expression, the functional relationships of the GH receptor, molecular biological analysis of the GH-GH receptor complex and proceeds to describe the insulin-like growth factor axis. Transgenic models are discussed for analysis of discrete effects. These discussions provide a bridge to clinically oriented discussions of growth abnormalities in GH deficient children, GH insensitivity due to deficiency of the GH receptor, and the concept of aging as a GH/IGF-I deficiency state. Discussions also include the immune system as a source and a responder to GH, GHRH, IGF-I and the effects of GH excess.

Human Growth Hormone Gene Expression in Pituitary and Placenta, N.E. Cooke and S.A. Liebhaber
Growth Hormone-Prolactin Receptor Gene Family, P.A. Kelly, M. Nagano, A. Sotiropoulos, J.-J. Lebrun, P. Touraine, L. Goujon, H. Dinerstein, F. Ferrag, H. Buteau, A. Pezet, N. Esposito, J. Finidori, M.-C. Postel-Vinay, and M. Edery
Rational Design of Potent Antagonists to the Human Growth Hormone Receptor, A.M. DeVos, M.H. Ultsch, A.A. Kossiakoff, G. Fuh, B.C. Cunningham, and J.A. Wells
The Insulin-Like Growth Factor (IGF) Axis, P. Cohen and R.G. Rosenfeld
Transgenic Mice in the Study of Growth Hormone and the Insulin-Like Growth Factors, A.J. D'Ercole
Clinical Aspects of Growth Hormone Treatment of Children, A.D. Rogol
Growth Hormone Receptor Deficiency, M.A. Vaccarello
Growth Hormone, IGF-I and Human Aging, R. Marcus and A. Hoffman
Effects of Human Growth Hormone in Older Adults, A.A. Abbasi and D. Rudman
Growth Hormone Effects on the Immune System, D.A. Weigent and J. Edwin Blalock
Spontaneous & Iatrogenic Hypersomatotropism, W.H. Daughaday
Author Index
Subject Index

Erscheint lt. Verlag 9.3.1995
Reihe/Serie Handbooks in Pharmacology and Toxicology ; 18
Zusatzinfo 3 Halftones, black and white; 13 Tables, black and white
Verlagsort Bosa Roca
Sprache englisch
Maße 156 x 234 mm
Gewicht 512 g
Einbandart gebunden
Themenwelt Medizinische Fachgebiete Innere Medizin Endokrinologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium 1. Studienabschnitt (Vorklinik) Histologie / Embryologie
ISBN-10 0-8493-8384-6 / 0849383846
ISBN-13 978-0-8493-8384-7 / 9780849383847
Zustand Neuware
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