Mitochondria in Health and Disease

Buch | Softcover

640 Seiten

2019
CRC Press (Verlag)
978-0-367-39269-7 (ISBN)

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It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles and their function, it became clear that mitochondrial malfunction could be linked to several chronic diseases. Diabetes has been associated with DNA mutation and can cause mutation itself. This text discusses findings involving the effects of disease on mitochondrial number, mitogenesis, and the base sequence of mitochondrial DNA. Experts discuss their study of mitochondria and what happens when it malfunctions. This book also explores the idea that mutated mitochondrial DNA can result in disease, and vice versa.

Carolyn D. Berdanier

Preface. Introduction to Mitochondria. Bioenergetics of Mitochondria. Mitochondrial Genome and Mitochondrial Function. Mitochondrial Diseases in Growth and Development. Using Mitochondria in Population Surveys. Mitochondrial DNA Mutation, Oxidative Stress and Alterations of Gene Expression in Human Aging. Mitochondrial Mutations in Vision. Mitochondrial DNA in Cardiomyopathies. Mitochondria in Diabetes. Drugs, Nutrients and Hormones in Mitochondrial Function. Bacterial F1F0ATP Synthase as a Model for Complex V. Cybrids and the Manipulation of Mitochondrial Genotype. Animal Modeling: From Transgenics to Transmitochondrial Models. BHE/Cdb Rats as Tools to Study Mitochondrial Mutation.

Erscheinungsdatum	18.09.2019
Verlagsort	London
Sprache	englisch
Maße	152 x 229 mm
Gewicht	1179 g
Themenwelt	Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
ISBN-10	0-367-39269-0 / 0367392690
ISBN-13	978-0-367-39269-7 / 9780367392697
Zustand	Neuware