HIV: Volume 1: Virology and Immunology
Oxford University Press (Verlag)
978-0-19-963492-7 (ISBN)
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AIDS is one of the most pressing medical emergencies of our era. Despite arguments to the contrary, the majority of AIDS researchers have agreed that there is a causal link between HIV infections and AIDS. However, it is now 12 years since the discovery of HIV and we are still a long way from understanding and controlling AIDS HIV 1 and HIV 2 are guides to studying HIV in the laboratory. HIV 1 describes studies of the virus and infected cells and covers techniques
for handling HIV safely, for studying viral entry, replication, and neutralization, and basic immunological techniques. HIV 2 explores the biochemistry and molecular biology of HIV, with a section on recent approaches to drug discovery.
HIV research is highly multidisciplinary so a complete compendium of all related methods would have been unreadable. Instead, these two volumes focues on the specialized techniques which are unique to studies of HIV. The books have been designed so that a novice entering HIV research can find clear instructions about how to perform standard experiments, such as assays for reverse transcriptase or antibodies to HIV. In addition the books include many novel methods which are described in
detail for the first time.
Section 1: Growth and isolation of HIV ; 1. Biological safety when working with HIV ; 2. Virological and molecular genetic techniques for studies of established HIV isolates ; 3. Isolation and biological characterization of primary HIV isolates ; 4. HIV infection of macrophages ; 5. HIV infection of dendritic cells ; 6. Vectors based on HIV ; Section 2: Analysis of HIV infection ; 7. Quantitative assays for virus neutralization ; 8. Detection of HIV entry into cells ; 9. Detection of viral DNA by PCR ; 10. Detection of viral RNA by PCR ; 11. Sequence analysis of virus variability based on PCR ; Section 3: Immunology ; 12. Humoral responses and detection during HIV infection ; 13. Quantification of CD4-positive T lymphocytes ; 14. CD-4 positive T-cell responses in HIV-1 infection ; 15. Lymphokine responses to HIV infection ; 16. HIV-1 specific cytotoxic T-lymphocyte responses and ADCC
| Erscheint lt. Verlag | 9.11.1995 |
|---|---|
| Reihe/Serie | Practical Approach Series ; 156 |
| Zusatzinfo | halftones, line figures, tables |
| Verlagsort | Oxford |
| Sprache | englisch |
| Maße | 155 x 236 mm |
| Gewicht | 526 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| ISBN-10 | 0-19-963492-0 / 0199634920 |
| ISBN-13 | 978-0-19-963492-7 / 9780199634927 |
| Zustand | Neuware |
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