Genomic Medicine

A Practical Guide

Laura J. Tafe, Maria E. Arcila (Herausgeber)

Buch | Hardcover

X, 325 Seiten

2019 | 1st ed. 2020
Springer International Publishing (Verlag)
978-3-030-22921-4 (ISBN)

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The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care.
This text focuses on clinical utility and validity and serves as an "owner's manual" in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.

Laura J. Tafe, MDAssociate Professor of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDartmouth-Hitchcock Medical CenterOne Medical Center DriveLebanon, NH 03756603-650-7211 Maria E. Arcila, MDAssociate attending Department of Pathology - Hematopathology and Molecular Diagnostics Services Memorial Sloan Kettering Cancer Center 1275 York AveNew York, NY 10065212 6397879

Pre-Analytics, Current Testing Technologies, and Limitations of Testing.- Next Generation Sequencing.- Cell Free DNA Testing.- Role of Bioinformatics in Molecular Medicine.- Interpreting Genomic Reports.- Lung Carcinoma.- GI including GIST.- Breast.- Genitourinary Tumors.- Gynecologic Malignancies.- Sarcomas.- Salivary Gland Carcinomas.- Sinonasal Carcinomas.- Acute Myeloid Neoplasms.- Chronic Myeloid Neoplasms.- Lymphomas.

Erscheinungsdatum	18.10.2019
Zusatzinfo	X, 325 p. 21 illus., 20 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	746 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Schlagworte	Drug targets • epigenetics • fish • hematopoietic disorders • immunotherapy • Pharmacogenomics
ISBN-10	3-030-22921-1 / 3030229211
ISBN-13	978-3-030-22921-4 / 9783030229214
Zustand	Neuware