A Handbook of Bioanalysis and Drug Metabolism
Taylor & Francis Ltd (Verlag)
978-0-415-27520-0 (ISBN)
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This stimulating new handbook examines the techniques, methodology and theory of bioanalysis and drug metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug-drug interactions. A Handbook of Bioanalysis and Drug Metabolism is an invaluable guide to senior undergraduates and postgraduates studying drug metabolism in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology - especially those considering industrial placements or a career in the biotechnology industry.
The Role of Drug Metabolism and Pharmacokinetics in Drug Discovery: Past, Present and Future. The Importance of the Physiochemical Properties of Drugs to Drug Metabolism. Sample Preparation. High Performance Liquid Chromatography in Pharmaceutical Bioanalysis. Quantitative Mass Spectronomy. Immunoassay in Bioanalysis. Phase I Metabolism. Phase II Enzymes. In vitro Techniques for Investigating Metabolism. Drug to Drug Interactions: an in vitro Approach. Clinical Impact of Drug Interactions. PreClinical Pharmacokinetics. Pharmacokinetic / Pharmacodynamic Modelling in PreClinical Drug Discovery. Toxicokinetics. Protein Binding in PlasmaA Case History of a Highly Protein Bound Drug. Metabolite Identification by Spectroscopy. Whole Body Autoradiography. Radiolabelled Studies in Man. Molecular Biology.
| Erscheint lt. Verlag | 11.11.2004 |
|---|---|
| Zusatzinfo | 130 Line drawings, black and white; 12 Illustrations, black and white |
| Verlagsort | London |
| Sprache | englisch |
| Maße | 174 x 246 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| ISBN-10 | 0-415-27520-2 / 0415275202 |
| ISBN-13 | 978-0-415-27520-0 / 9780415275200 |
| Zustand | Neuware |
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