Pharmaceutical Biotechnology

Fundamentals and Applications, Second Edition

Daan J. a. Crommelin, Robert D. Sindelar (Herausgeber)

Buch | Softcover

456 Seiten

2002 | 2nd New edition
Informa Healthcare (Verlag)
978-0-415-28501-8 (ISBN)

Infos

Pharmaceutical biotechnology is a rapidly evolving subject. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for a spectrum of serious diseases. This textbook provides coverage of the basic science and applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use.

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The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.

Inhalt

Molecular Biotechnology. Biophysical and Biochemical Analysis of Recombinant Proteins Structure and Analysis of Proteins. Production and Downstream Processing of Biotech Products. Formulation of Biotech Products, Including Biopharmaceutical Considerations. Pharmacokinetics and Pharmacodynamics of Peptide and Protein Drugs. Genomics, Proteomics and Additional Biotechnology-Related Techniques. Gene Therapy. Hematopoietic Growth Factors. Interferons and Interleukins. Insulin. Growth Hormones. Vaccines. Monoclonal Antibody-Based Pharmaceuticals. Appendix A: Trastuzumab/Herceptin. Appendix B: Abciximab/ReoPro. Appendix C: Daclizumab/Zenapax and Basiliximab/Simulect. Recombinant Thrombolytic Agents. Recombinant Coagulation Factors. Recombinant Human Deoxyribonuclease. Follicle-Stimulating Hormone. Dispensing Biotechnology Products: Handling, Professional Education and Product Information. Economic Considerations in Medical Biotechnology. Biotechnology Products in the Pipeline.

Produkt-Details

• Erscheint lt. Verlag: 14.11.2002
• Sprache: englisch
• Maße: 216 x 279 mm
• Gewicht: 1656 g
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• ISBN-10: 0-415-28501-1 / 0415285011
• ISBN-13: 978-0-415-28501-8 / 9780415285018
• Zustand: Neuware