Chemotherapy for Leukemia
Springer Verlag, Singapore
978-981-10-9844-4 (ISBN)
This work facilitates a comprehensive understanding of modern treatment methodology for leukemia. The volume therefore will greatly benefit not only hematologists but also oncologists, all physicians who specialize in blood cancer, and pharmacologists who are involved in the development of therapeutic agents for leukemia.
Takanori Ueda Vice-President, University of Fukui Faculty of Medical Sciences, 3-9-1 Bunkyo, Fukui 910-8507, Japan
1 An Overview.- Part I Bcr-Abl Tyrosine Kinase Inhibitors (TKIs).- 2 Imatinib: Basic Results.- 3 Imatinib: Clinical Pharmacology and Therapeutic Results.- 4 Dasatinib, Nilotinib, Bosutinib, Ponatinib, and Other TKIs.- Part II New Antibodies for Leukemia.- 5 Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Basic Results.- 6 Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Clinical Pharmacology and Therapeutic Results.- 7 Inotuzumab Ozogamicin for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results.- 8 Blinatumomab for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results.- 9 Mogamulizumab in Adult T-cell Leukemia/Lymphoma.- Part III Signaling inhibitors.- 10. FLT3 inhibitors.- Part IV Differentiating Agents.- 11 Retinoic Acid, All-Trans Retinoic Acid (ATRA) and Tamibarotene.- 12 The Molecular Basis of Arsenic Trioxide Treatment for Acute Promyelocytic Leukemia (APL).- 13 Arsenic Trioxide: Clinical Pharmacology and Therapeutic Results.- Part V New Chemotherapeutic Agents Including Antimetabolite.- 14 Nelarabine.- 15 Forodesine.- 16 Clofarabine: Structure, Mechanism of Action, and Clinical Pharmacology.- 17 Clinical Use of Clofarabine for Adults and Children with Leukemia.- 18 Re-Emerging Antimetabolites with Novel Mechanism of Action with Respect to Epigenetic Regulation: Basic Aspects.- 19 Epigenetic Regulator, Re-Emerging Antimetabolites with Novel Mechanism of Action (Azacitidine and Decitabine): Clinical Pharmacology and Therapeutic Results.- Part VI Therapy Targeting Leukemic Stem Cells.- 20 Therapies Targeting Leukemic Stem Cells.
Erscheint lt. Verlag | 11.9.2018 |
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Zusatzinfo | 51 Illustrations, color; 31 Illustrations, black and white; VIII, 361 p. 82 illus., 51 illus. in color. |
Verlagsort | Singapore |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hämatologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
Schlagworte | Acute promyelocytic leukemia • antimetabolite analogues • chemokine receptor 4 • Chronic Myeloid Leukemia • epigenetic regulator • Leukemic Stem Cells • Molecular targeted agent • signaling inhibitors |
ISBN-10 | 981-10-9844-1 / 9811098441 |
ISBN-13 | 978-981-10-9844-4 / 9789811098444 |
Zustand | Neuware |
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