General and Applied Toxicology
Nature Publishing Group (Verlag)
978-0-333-49801-9 (ISBN)
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This two-volume work gives comprehensive coverage of the scientific basis of toxicology and its applications. Both general and specialist needs are considered, with particular reference to basic principles, definitions, laboratory aspects, interpretations of data and practical applications of toxicology. Thus, there are sections devoted to basic concepts, techniques, toxicity by specific routes of exposure and by organ system, special aspects of toxicology, and the increasingly dominant area of regulatory toxicology. The book is designed so that it can be used as a sole or main text for course work for examinations such as those of the Royal College of Pathologists, Institute of Biology and American Board of Toxicology. It contains work by 70 international contributors.
Volume I General aspects. Part 1 Introductory and basic material: fundamentals of toxicology, B. Ballantyne et al; statistics for toxicology, P.N. Lee; principles of testing for acute toxic effects, C. Rhodes et al; biotransformation of xenobiotics, J. Timbrell; toxicokinetics, A.G. Renwick; physiologically-based pharmacokinetic modeling, Hon-Wing Leung; biochemical mechanisms of toxicology, J. Caldwell; alternatives to in vivo studies in toxicology, S.C. Gad; acute non-specific toxicity, J.A. Henry and S.L. Cassidy; information resources for toxicology, J. Deschamps and Morgan. Part 2 Techniques in toxicity: design of toxicology studies, A. Paine; pathological techniques in toxicology, P. Greaves; haematology in toxicology studies, D. Woodman and J. Fuller; clinical chemistry in toxicology studies, M. Stonard and Evans; antidotal studies, N. Bateman and T.C. Marrs; quality assurance in toxicology studies, T.R. Stiles; hazards in the toxicology laboratory, B. Ballantyne; evaluation of toxicity in human subjects, P.N. Bennett. Part 3 Toxicity by routes: parental toxicity, D. Walker peroral toxicity, T.R. Tyler; percutaneous toxicity, Hon-Wing Leung; inhalation toxicity, P. Hext and I.P. Bennett. Volume II Organ and special toxicity - applied toxicology. Part 1 Target organ toxicity: neurotoxicity, J.N. LeFauconnier; peripheral sensory irritation, B. Ballantyne nephrotoxicity, B.A. Lock; systemic pulmonary toxicity, J.P. Kehrer; pulmonary hypersensitivity reactions, H.C. Lewinsohn and H.D. Burleigh-Flayer ophthalmic toxicology, B. Ballantyne; cardiovascular toxicity, S.I. Baskin heptotoxicity, P. Grasso and R.H. Hinton; toxicity of the pancreas, J.M. Braganza; toxicology of skeletal muscle, K.E. Misulis et al; toxicology of bone, A.G.B. Lansdowne; cutaneous toxicity, S.J. Hermansky; ototoxicity, Forge and E.S. Harper, toxicology of the adrenal, thyroid and endocrine pancreas, J.A. Thomas; immunotoxicology, K. Miller and C. Neredith; haematotoxicology, J. Amess. Part 2 Special toxicology: mutagenicity, A. Tweats; cytogenetics, D. Anderson; chemical carcinogenesis (genotoxic), D.B. McGregor; chemical carcinogenesis (epigenetic), C. Berry; Reproductive toxicology, J.N. Ratcliffe and F. Sullivan; developmental toxicology, R.W. Tyl; neonatal toxicology, S. Kacew. Part 3 Regulatory tocicology: overview of regulatory agencies, G. Diggle; regulation of drugs in Europe and the United Kingdom, R.D. Mann; regulation of drugs on the North American continent, M.B. Vernoy; regulation of veterinary product in Europe and the United Kingdom, K. Woodward; regulation of veterinary products in the United States, K. Woodward; regulation of industrial chemicals and pesticides in Europe and the United Kingdom, R. Fielder and Martin; regulation of food additives and food contact materials on the North American continent, M.B. Vernoy. Part 4 Toxicology in special situations: pharmaceutical toxicology, P.F. D'Arcy; medical devices, Adams. Part contents.
| Erscheint lt. Verlag | 19.11.1993 |
|---|---|
| Zusatzinfo | index |
| Verlagsort | London |
| Sprache | englisch |
| Maße | 189 x 246 mm |
| Gewicht | 500 g |
| Themenwelt | Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie |
| ISBN-10 | 0-333-49801-1 / 0333498011 |
| ISBN-13 | 978-0-333-49801-9 / 9780333498019 |
| Zustand | Neuware |
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