Advances in RAB Research

2nd Symposium on Regulatory Autoantibodies Targeting G-Protein-Coupled Receptors - Book of Abstracts

Gabriela Riemekasten, Anja Kerstein (Herausgeber)

Buch | Softcover

120 Seiten

2018
Infinite Science Publishing (Verlag)
978-3-945954-51-5 (ISBN)

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This book concludes the results of the 2nd symposium on functional or regulatory autoantibodies targeting G-protein-coupled receptors (GPCRs) in Lübeck in 2018. GPCRs are involved in a variety of physiological and pathophysiological processes. So far, much effort has been made on anti-GPCR drug discovery with a focus on the development of small molecules for the treatment of cancer, infection, metabolic disorders or inflammatory diseases. Recently, functional autoantibodies against GPCRs were identified in healthy donors and were found to be dysregulated in various diseases. They are associated with pathogenesis, uncovering a potential new field of therapeutic intervention. Thus, the aim of the symposium in 2018 was to combine the current knowledge about the role of anti-GPCR ab in different pathologies, their mode of action and state-of-the-art research techniques to identify common fundamental pathways that can be transferred to other disease entities with similar manifestations.

Erscheinungsdatum	30.09.2018
Verlagsort	Lübeck
Sprache	englisch
Maße	173 x 245 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Rheumatologie
Themenwelt	Medizin / Pharmazie ► Studium
Schlagworte	Anti-GPCR drug discovery • Development of small molecules and monoclonal antibodies • Treatment of cancer, infection, metabolic disorders or inflammatory diseases
ISBN-10	3-945954-51-7 / 3945954517
ISBN-13	978-3-945954-51-5 / 9783945954515
Zustand	Neuware