Toxicology of Herbal Products
Springer International Publishing (Verlag)
978-3-319-82915-9 (ISBN)
This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities.
With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.
Olavi Pelkonen Professor of Pharmacology (emeritus) and Previous Head of the Department Department of Pharmacology and Toxicology, University of Oulu, Oulu, Finland. Olavi Pelkonen has MD, PhD degree from the University of Oulu, Finland. In 1978-2010 he was Associate and Full Professor of Pharmacology as well as Head of the Department in Oulu, Finland. He has 300 original and review articles in international scientific journals, mainly on various aspects of drug and carcinogen metabolism, especially by cytochrome P450 enzymes, and their regulation by genetic and environmental factors. During the last 10 years, he was a co-opted toxicology expert at Committee of Herbal Medicinal Products of European Medicines Agency.
Toxicity of Herbal Medicines - From Past to Present and Future.- History and current status of Herbal Medicines.-Composition and quality control of herbal products.- Toxicokinetics of herbal products.- Interactions between conventional and herbal medicinal products.- Safety Pharmacology of herbal products.- Systems Network Pharmaco-Toxicology in the Study of Herbal Medicines.- Metabolomics applications in herbal medicine.-Genotoxicity and carcinogenicity of herbal products.- Teratogenicity and developmental toxicity of herbal products.- Sensitization and allergies of herbal products.- Herbal Hepatotoxicity.-Nephrotoxicity of herbal products.- Herbal neurotoxicity: an introduction to its occurrence and causes.- Cardiovascular toxicities of herbal products: an overview of selected compounds.- Clinical Perspectives in Diagnostic-omics and Personalised Medicine approach to monitor effectiveness and toxicity of Phytocomplexes.
"This comprehensive book on herbal product toxicology covers the history of herbal products to the role of systems biology in evaluating the toxicity of complex mixtures. ... It is a timely and much-needed book for beginner toxicologists. It is suitable for students, researchers, and anyone who would like to have a quick introduction to this subject. ... I would recommend this book for a quick glance of this field." (Vijaykumar P. Kale, Doody's Book Reviews, September, 2017)
| Erscheint lt. Verlag | 20.7.2018 |
|---|---|
| Zusatzinfo | XVI, 479 p. 53 illus., 26 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 1012 g |
| Themenwelt | Medizin / Pharmazie ► Naturheilkunde |
| Medizin / Pharmazie ► Pharmazie | |
| Naturwissenschaften ► Chemie ► Technische Chemie | |
| Technik | |
| Schlagworte | genotoxicity • herbal medicine • Metabolomics • Pharmacokinetics • Teratogenicity • Toxicity hazards |
| ISBN-10 | 3-319-82915-7 / 3319829157 |
| ISBN-13 | 978-3-319-82915-9 / 9783319829159 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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