Plasma Cell Dyscrasias

Aldo M. Roccaro, Irene M. Ghobrial (Herausgeber)

Buch | Softcover

VI, 361 Seiten

2018 | 1. Softcover reprint of the original 1st ed. 2016
Springer International Publishing (Verlag)
978-3-319-82078-1 (ISBN)

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This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström's macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.

MGUS and smoldering myeloma.- Multiple Myeloma.- Primary amyloidosis, systemic light chain and heavy chain diseases plasmacytoma.- Waldenstrom's Macroglobulinemia.

Erscheinungsdatum	05.03.2022
Reihe/Serie	Cancer Treatment and Research
Zusatzinfo	VI, 361 p. 9 illus., 7 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	563 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Schlagworte	Bone marrow microenvironment • Genetics • multiple myeloma • Plasma cell dyscrasias • therapies
ISBN-10	3-319-82078-8 / 3319820788
ISBN-13	978-3-319-82078-1 / 9783319820781
Zustand	Neuware