Handbook of Biologics & Biosimilars in Dermatology
Jaypee Brothers Medical Publishers (Verlag)
978-93-5270-364-7 (ISBN)
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A drug is typically manufactured through chemical synthesis, which means that it is made by combining specific chemical ingredients in an ordered process. Biologics are medicines made from living cells through highly complex manufacturing processes and must be handled and administered under carefully monitored conditions. Biologics are used to prevent, treat, diagnose, or cure a variety of diseases including cancer, chronic kidney disease, autoimmune disorders, and infectious diseases. A biosimilar is a biologic that is similar to another biologic drug already that has already been approved.
This book is a complete guide to the use of biologics and biosimilars in the treatment of dermatologic disorders.
Beginning with an overview of the history and classification of biologics and the concept of biosimilars, the following chapters explain their therapeutic use for different skin conditions.
The final sections cover related topics such as cost effectiveness and quality of life with biologic therapy, and the book concludes with discussion on future developments and the use of small molecule treatment.
Key points
Complete guide to use of biologics and biosimilars in treatment of dermatologic disorders
Covers many different skin diseases and conditions
Discusses related topics such as cost effectiveness and quality of life
Covers future development of small molecule therapy
Manas Chatterjee MD DNB Senior Adviser, Professor and Head, Department of Dermatology, INHS Asvini, Mumbai, Maharashtra, India Shekhar Neema MD Assistant Professor, Department of Dermatology, Command Hospital, Kolkata, West Bengal, India
History and Development of biologics
Classification of Biologics
Concept and development of biosimilars
Biologics in management of psoriasis – Pathogenesis and mechanism of action
TNF alpha Blockers
Etanercept Infliximab
Adalimumab
IL-17 blockers – Secukinumab
Anti CD6 monoclonal antibody
Newer biologics
Anti CD20 monoclonal antibody
Anti IgE monoclonal antibody
Intravenous immunoglobulins
Miscellaneous uses of biologics
Biologic approach to management of various diseases – when to use and which one?
Psoriasis
Immunobullous diseases
Hidradenitis suppurativa
Connective tissue diseases
Adverse effects of biologics – feared or real?
Management of latent tuberculosis infection
Adult immunization prior to initiation of biologic therapy
Cost effectiveness and quality of life with biologic therapy
Biologics in children: Which, when, why?
Biologics in presence of hepatitis B and C infection
Biologics in special situation
Small molecules
Tofacitinib
Apremilast
Sirolimus
| Erscheinungsdatum | 10.05.2021 |
|---|---|
| Verlagsort | New Delhi |
| Sprache | englisch |
| Maße | 159 x 241 mm |
| Gewicht | 250 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie |
| ISBN-10 | 93-5270-364-2 / 9352703642 |
| ISBN-13 | 978-93-5270-364-7 / 9789352703647 |
| Zustand | Neuware |
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