Cancer Immunosurveillance
Humana Press Inc. (Verlag)
978-1-4939-8884-6 (ISBN)
Cutting-edge and thorough, Cancer Immunosurveillance: Methods and Protocols is a valuable resource to aid researchers in better understanding and experimenting in this exciting and developing field.
Usage of Droplet Digital PCR (ddPCR) Assays for T Cell Quantification in Cancer.- An Economical, Quantitative, and Robust Protocol for High Throughput T Cell Receptor Sequencing from Tumor or Blood.- Generation of Tumor Antigen-Specific Cytotoxic T Lymphocytes from Pluripotent Stem Cells.- Expansion and Adoptive Transfer of Human Vδ2+ T Cells to Assess Anti-Tumor Effects In Vivo.- Usage of Single-Cell RNA-Sequencing to Unveil Immune Lymphoid Cell Precursors.- Isolation, Expansion, and Characterization of Natural Killer Cells and Their Precursors as a Tool to Study Cancer Immunosurveillance.- CD107a Degranulation Assay to Evaluate Immune Cell Anti-Tumor Activity.- A Flow Cytometric NK Cell-Mediated Cytotoxicity Assay to Evaluate Anti-Cancer Immune Responses In Vitro.- Mouse Models to Study Natural Killer Cell-Mediated Immunosurveillance and Metastatic Latency.- Tumor-Associated Macrophage Isolation and In Vivo Analysis of their Tumor Promoting Activity.- Conditional Genetic Ablation Mouse Models as a Tool to Study Cancer Immunosurveillance In Vivo.- Determination and Isolation of Immune Populations from Brain Tumor Microenvironments.- Mouse Model of Colitis Associated Colorectal Cancer (CAC): Isolation and Characterization of Mucosal-Associated Lymphoid Cells.- Cancer Exome-Based Identification of Tumor Neo-Antigens Using Mass Spectrometry.- Single-Cell Mass Cytometry of Archived Human Epithelial Tissue for Decoding Cancer Signaling Pathways.- Purification of Leukemia-Derived Exosomes to Study Microenvironment Modulation.- Molecular Characterization of Circulating Tumor Cells to Study Cancer Immunoevasion.- Quantitative Identification of Senescent Cells in Cancer.- Generation and Harnessing of Heterotypic Tumor-Stroma Spheroids to Study Cancer Immunosurveillance.- Establishment of Slice Cultures as a Tool to Study the Cancer Immune Microenvironment.- Gold StandardAssessment of Immunogenic Cell Death in Oncological Mouse Models.- A Novel Dendritic Cell-Based Vaccination Protocol to Stimulate Immunosurveillance of Aggressive Cancers.- Development of Bi-Specific Antibody Derivatives for Cancer Immunotherapy.- Generation of CAR-T Cells for Cancer Immunotherapy.
Erscheinungsdatum | 19.11.2018 |
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Reihe/Serie | Methods in Molecular Biology ; 1884 |
Zusatzinfo | 63 Illustrations, color; 13 Illustrations, black and white; XIII, 363 p. 76 illus., 63 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Studium | |
Schlagworte | immune receptors • NK cell-mediated cytotoxicity • Oncoimmunology • T cell exhaustion • Tumor |
ISBN-10 | 1-4939-8884-0 / 1493988840 |
ISBN-13 | 978-1-4939-8884-6 / 9781493988846 |
Zustand | Neuware |
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