Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants (eBook)

James A. Dykens, Yvonne Will (Herausgeber)

eBook Download: PDF

2018 | 1. Auflage
816 Seiten
Wiley (Verlag)
978-1-119-32973-2 (ISBN)

Infos

Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. Covers both basic science and applied technology / methods Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria

Autor

Yvonne Will, PhD, is a Senior Director and the Head of Science and Technology Strategy, Drug Safety Research and Development at Pfizer, Connecticut, USA. In addition to the prior edition of this book, she co-edited Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers(Wiley, 2016). James A. Dykens, PhD, oversees EyeCyte Therapeutics, a start-up developing treatments for progressive blinding diseases via targeting mitochondrial dysfunction. He co-edited the first edition of this book.

Produkt-Details

• Erscheint lt. Verlag: 21.3.2018
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
• Themenwelt: Naturwissenschaften ► Chemie
• Schlagworte: Biowissenschaften • Cell & Molecular Biology • Chemie • Chemistry • Life Sciences • Medical Science • Medizin • Pharmacology & Pharmaceutical Medicine • Pharmakologie u. Pharmazeutische Medizin • Toxicology • Toxikologie • Zell- u. Molekularbiologie
• ISBN-10: 1-119-32973-6 / 1119329736
• ISBN-13: 978-1-119-32973-2 / 9781119329732