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Expmtl Toxicology The Basic Issues

Expmtl Toxicology The Basic Issues

Buch | Hardcover
566 Seiten
1994 | 2nd New edition
Royal Society of Chemistry (Verlag)
978-0-85186-451-8 (ISBN)
CHF 156,25 inkl. MwSt
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This collection of research papers covers various topics in toxicology, including the metabolism and disposition of xenobiotics, immunotoxicology, the theory and practice in metabolic studies, genetic toxicology, molecular toxicology, experimental design and ethics in animal testing.
This volume addresses the basic issues concerned with the practice of experimental toxicology and discusses such issues as experimental design, biochemical issues, animal husbandry, species differentiation, carcinogenesis and laboratory design. It has been revised and updated to give special attention to recent advances in the areas of molecular, genetic and reproductive toxicology and in the knowledge regarding the multiplicity of enzymes involved in foreign compound metabolism.

40 years research into the biology and pathology of the skin and its response to injury. Research into the nutrition and physiology of trace and xenbiotic metals in the skin. Study of intrinsic cytoprotective mechanisms against metal toxicity. Special studies onthe biological value of silver in wound care and as an antimicrobial agent in medical devices. International consultant and lecturer. Published 250 scientific papers and book chapters.

Effects of physical form, route and species, A. Wilson; influence of animal species, strain, age, hormonal and nutritional status, F. Roe; experimental design, A. Wilson; the biochemical principles of toxicology, W. Aldridge; animal husbandry, A. Lansdown; inhalation toxicology, R. Riley and D. Conning; histopathology in safety evaluation, J. Evans and W. Butler; the metabolism and disposition of xenobiotics, S. Gangoli and J. Phillips; theory and practice in metabolic studies, J. Phillips and S. Gangoli; immunotoxicology - conceptual problems, H. Amos; perspectives - the evaluation of reproductive toxicity and teratogenicity, A. Lansdown; genetic toxicology, D. Anderson; molecular toxicology, P. Rumsby; testing for carcinogenicity, P. Grasso; in vitro methods for teratology testing, D. Anderson; assessing chemical injury in the reproductive system, S. Gangoli and J. Phillips; statistics, P. Lee; risk assessment of chemicals, D. Lovell; epidemiology, G. Paddle; information and consultancy services in toxicology, D. Conning; regulations and advisory requirements in relation to food, D. Conning; the influence of a growing environmental awareness on toxicology laboratory design, D. Anderson and B. Copeland; good laboratory practice, R. Hawkins; ethics in experiments on animals, D. McGregor.

Erscheint lt. Verlag 27.1.1994
Verlagsort Cambridge
Sprache englisch
Maße 156 x 235 mm
Themenwelt Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
Naturwissenschaften Biologie Biochemie
ISBN-10 0-85186-451-1 / 0851864511
ISBN-13 978-0-85186-451-8 / 9780851864518
Zustand Neuware
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