Prostate Cancer

Methods and Protocols

Buch | Hardcover

264 Seiten

2018 | 1st ed. 2018
Humana Press Inc. (Verlag)
978-1-4939-7843-4 (ISBN)

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This volume presents methods and protocols on modern analysis of steroid receptor and prostate cancer function. Chapters detail androgen, androgen receptor action, anti-androgen enzalutamide, in vitro and in vivo models, imaging, gene fusions, and help facilitate studies with novel drugs including anti-androgens and chemotherapeutics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Prostate Cancer: Methods and Protocols aims to provide easily reproducible techniques.

Generation of Prostate Cancer Patient-derived Xenografts to Investigate Mechanisms of Novel Treatments and Treatment Resistance.- Methods to Study Angiogenesis in a Mouse Model of Prostate Cancer.- Methodologies Applied to Establish Cell Cultures in Prostate Cancer.- Protocols for Migration and Invasion Studies in Prostate Cancer.- Transplantable Animal Studies and Whole-body Optical Imaging in Prostate Carcinoma.- Protocols for Tissue Microarrays in Prostate Cancer Studies.- Functional Studies on Steroid Receptors.- Protocols for Studies on TMPRSS/ERG in Prostate Cancer.- Protocols for the Study of Taxanes Chemosensitivity in Prostate Cancer.- A Method for Prostate and Breast Cancer Cell Spheroid Cultures using Gelatin Methacryloyl-based Hydrogels.- Protocols for Studies on Genetically Engineered Mouse Models in Prostate Cancer.- Protocols for Studies on Stromal Cells in Prostate Cancer.- Techniques for Evaluation of AR Transcriptional Output and Recruitment to DNA.- NMR-based Prostate Cancer Metabolomics.- Studies on Steroid Receptor Coactivators in Prostate Cancer.

Erscheinungsdatum	07.06.2018
Reihe/Serie	Methods in Molecular Biology ; 1786
Zusatzinfo	40 Illustrations, color; 5 Illustrations, black and white; XI, 264 p. 45 illus., 40 illus. in color.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Themenwelt	Medizin / Pharmazie ► Studium
Schlagworte	androgen receptor • anti-androgen enzalutamide • Chemotherapeutics • Oncogenes • steroid receptor function • Xenograft models
ISBN-10	1-4939-7843-8 / 1493978438
ISBN-13	978-1-4939-7843-4 / 9781493978434
Zustand	Neuware