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Head and Neck Cancers -

Head and Neck Cancers

Evidence-Based Treatment
Buch | Hardcover
550 Seiten
2018
Springer Publishing Co Inc (Verlag)
978-0-8261-3777-7 (ISBN)
CHF 369,95 inkl. MwSt
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Head and Neck Cancers presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with Oropharyngeal Cancers, Cancers of the Oral Cavity, Laryngeal Cancers, Nasopharyngeal Cancers, Hypopharyngeal Cancers, Cancers of the Sinuses and the Skull Base, Salivary Gland Cancers, and Lymphadenopathies.
“Overall, this is an excellent book on an important topic in cancer that medical oncologists, pharmacologists, and nurses, as well as related healthcare professionals, may find very helpful.”

Score: 100, 5 Stars, Doody’s Medical Reviews

Head and Neck Cancers: Evidence-Based Treatment presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with head and neck cancers, including oropharyngeal cancer, cancer of the oral cavity, laryngeal cancer, nasopharyngeal cancer, hypopharyngeal cancer, cancer of the sinuses and the skull base, salivary gland cancer, and neck lymphadenopathy.

Section 1 of the book covers the most pertinent details on the epidemiology, biology, diagnosis and staging of the disease including topics such as the genomic landscape of squamous cell carcinoma of the head and neck and novel imaging modalities. Section 2 discusses the evidence-based treatment modalities for conventional and novel chemotherapy regimens, the evidence behind emerging radiation therapy techniques and the minimally invasive surgical advances changing the landscape of care. The chapters in Section 3 are dedicated to site-specific management, including management guidelines, tables with FDA-approved therapies and relevant ongoing clinical trials as well as instructive clinical cases with important discussion on outcomes and follow up care. Finally, Section 4 focuses on recurrent and metastatic disease and Section 5 provides the essentials on supportive care, including managing the elderly, managing patients suffering from dysphagia and oral complications, and must-know details of quality of life assessment and patient-reported outcomes.

Emphasizing the practice-changing techniques and the latest evidence-based treatment advances including targeted therapies, immunotherapy, transoral robotic surgery, and radiation therapy precision, this comprehensive yet accessible textbook is indispensable for any clinical oncologist of each discipline wanting a balanced and evidence-based reference on managing patients with head and neck malignancies.

Key Features:



Includes didactic clinical cases for each type of head and neck cancer
Numerous tables highlight FDA approved therapies and ongoing clinical trials
Provides evidence-based recommendations for treating head and neck cancers at each stage of the disease with conventional and novel treatment strategies
Covers strategies for managing acute and late complications to treatment
Includes access to the fully-searchable downloadable e-book

Athanassios Argiris, MD, FACP is Professor, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania. Robert L. Ferris, MD, PhD, FACS, UPMC Endowed Professor and Vice-Chair, Departments of Otolaryngology, of Immunology, and of Radiation Oncology and Chief, Division of Head and Neck Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania David I. Rosenthal, MD, FACR, FASTRO, Professor of Radiation Oncology and Head and Neck Surgery, and Chief of the Head and Neck Radiation Oncology Service, University of Texas MD Anderson Cancer Center, Houston, Texas

Contents


Contributors


Preface


SECTION I


Epidemiology, Biology, Diagnosis, and Staging


1. Head and Neck Cancer Epidemiology


Angela L. Mazul, Erich M. Sturgis, Andrew F. Olshan, and Jose P. Zevallos


2. Pathology of HNSCC


Michelle D. Williams and Adel K. El-Naggar


3. The Genomic Landscape of HNSCC


Steffen Wagner, Jens P. Klussmann, and Ruud H. Brakenhoff


4. HPV-Related Head and Neck Cancer Biology


Farhoud Faraji and Carole Fakhry


5. Imaging of Head and Neck Cancers


Rathan M. Subramaniam


SECTION II


Established and Emerging Treatment Modalities


6. Advances in Radiation Therapy Techniques for HNSCC: Image-Guided RT Stereotactic, IMRT-VMAT, MRI-Linac and Simulation


Jussi Sillanpaa, C. Jillian Tsai, and Nancy Y. Lee


7. Proton Therapy


Pierre Blanchard, G. Brandon Gunn, and Steven J. Frank


8. Transoral Robotic Surgery: Advances and Applications


Meghan T. Turner, F. Christopher Holsinger, and Robert L. Ferris


9. Induction Chemotherapy: Current and Emerging Role in HNSCC


Glenn J. Hanna and Robert I. Haddad


10. Immunotherapy for HNSCC: Rationale and Clinical Applications


Jennifer Moy, Jennifer M. Johnson, Jessica Moskovitz, Robert L. Ferris, and Athanassios Argiris


11. Targeting the Human Epidermal Receptor Family in HNSCC


Emmanuel Seront, Sandra Schmitz, and Jean-Pascal Machiels


12. Therapies Targeting VEGF/Angiogenesis and Other Novel Targets and Therapies in HNSCC


Sophie Stock-Martineau, Yanqun Dong, Denis Soulières, and Thomas J. Galloway


SECTION III


Site-Specific Management


13. Oropharyngeal Cancer: HPV-Positive Disease


Christien A. Kluwe, Anthony J. Cmelak, and Barbara A. Burtness


14. Non–HPV-Associated Oropharyngeal Cancer


Meghan T. Turner, Anirudh Saraswathula, and F. Christopher Holsinger


15. Oral Cavity Cancer: Surgical Approaches and Postoperative Treatment


Antoine Eskander, Jacques Bernier, Lisa Licitra, Paolo Bossi, and Theodoros N. Teknos


16. Nasopharyngeal Cancer


Wai Tong Ng, Oscar S. H. Chan, Henry C. K. Sze, Ka On Lam, and Anne W. M. Lee


17. Hypopharyngeal Cancer: A Multidisciplinary Approach


Moran Amit, Loren K. Mell, Cristina P. Rodriguez, and Neil D. Gross


18. Laryngeal Cancer: Organ Preservation Strategies


Arlene A. Forastiere, Jae Lee, Steven B. Chinn, Karim Boudadi, Avraham Eisbruch, Randal S. Weber


19. Malignancies of the Paranasal Sinuses and Skull Base


Heather A. Osborn, Jong Chul Park, Nabil F. Saba, Pierre Blanchard, and Derrick T. Lin


20. Evaluation and Treatment of Metastatic Lymphadenopathy From an Unknown Primary


Shirin Attarian, Richard Blake Ross, Shlomo A. Koyfman, and Missak Haigentz, Jr.


21. Salivary Gland Malignancies


Cristina P. Rodriguez, Jessica L. Geiger, Jon Mallen-St. Clair, Patrick K. Ha, Sue S. Yom, Adam S. Garden, and David J. Adelstein


SECTION IV


Recurrent or Metastatic Disease


22. Locally Recurrent HNSCC: Salvage Surgery, Reirradiation


Antoine Eskander, Sharon A. Spencer, Corey J. Langer, Takashi Maruo, Ryuichi Hayashi, Sadamoto Zenda, and James W. Rocco


23. Recurrent or Metastatic HNSCC: Systemic Therapy


Tomohiro Enokida, Susumu Okano, and Makoto Tahara


SECTION V


Supportive Care and Special Patient Groups


24. Oral Complications


Rajesh V. Lalla and Douglas E. Peterson


25. Dysphagia in Patients With Head and Neck Cancer


Katherine A. Hutcheson and Jan S. Lewin


26. Quality of Life Assessment and Patient-Reported Outcomes in Head and Neck Cancer


Minh Tam Truong and Lisa Ann Kachnic


27. Management of Head and Neck Cancers in the Elderly


Jessica L. Geiger and Julie E. Bauman


Index

Erscheinungsdatum
Zusatzinfo 60 Illustrations
Verlagsort New York
Sprache englisch
Maße 178 x 254 mm
Gewicht 454 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete HNO-Heilkunde
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Nuklearmedizin
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
ISBN-10 0-8261-3777-6 / 0826137776
ISBN-13 978-0-8261-3777-7 / 9780826137777
Zustand Neuware
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