Molecular Pathology of Lung Diseases
Springer-Verlag New York Inc.
978-1-4939-5040-9 (ISBN)
The first two sections of the volume provide the reader with general concepts, terminology and procedures in molecular pathology. The remainder of the volume is subdivided into neoplastic and non-neoplastic lung diseases with detailed chapters covering the current molecular pathology of specific diseases.
Basic Concepts of Molecular Pathology.- Genes, Gene Products, and Transcription Factors.- Receptors, Signaling Pathways, Cell Cycle, and DNA Damage Repair.- Cell Adhesion Molecules.- Apoptosis and Cell Death: Relevance to Lung.- Roles of Mutation and Epimutation in the Development of Lung Disease.- Techniques and Experimental Systems in Molecular Pathology.- Bioinformatics and Omics.- General Approach to Molecular Pathology.- Applications of Molecular Tests in Anatomic Pathology.- Polymerase Chain Reaction and Reverse Transcription&##x2014;Polymerase Chain Reaction.- Array Comparative Genomic Hybridization in Pathology.- Loss of Heterozygosity in Lung Diseases.- In Situ Hybridization: Principles and Applications for Pulmonary Medicine.- Proteomics.- Animal Models of Lung Disease.- Tissue Culture Models.- Molecular Pathology of Pulmonary and Pleural Neoplasms: General Principles.- Molecular Oncogenesis of Lung Cancer.- Genetic Susceptibility.- Prognostic Markers.- Pulmonary Angiogenesis in Neoplastic and Nonneoplastic Disorders.- Lung Cancer Stem Cells.- Gene Therapy Approaches for Lung Cancer.- Response to Conventional Therapy and Targeted Molecular Therapy.- Environmental Agents in Lung and Pleural Neoplasms.- Viral Oncogenesis.- Molecular Pathology of Pulmonary and Pleural Neoplasms: Specific Histologic Types.- Adenocarcinoma and Its Precursor Lesions.- Molecular Pathology of Squamous Cell Carcinoma and Its Precursors.- Molecular Pathology of Large Cell Carcinoma and Its Precursors.- Small Cell Carcinoma.- Neuroendocrine Carcinomas and Precursors.- Pulmonary Lymphomas.- Posttransplantation Lymphoproliferative Disorder.- Unusual Benign and Malignant Neoplasms of Lung: Molecular Pathology.- Primary Versus Metastatic Cancer: Gene Expression Profiling.- Diffuse MalignantMesothelioma: Genetic Pathways and Mechanisms of Oncogenesis of Asbestos and Other Agents That Cause Mesotheliomas.- Molecular Pathology of Pediatric Tumors of the Lung.- Molecular Pathology of Pulmonary Infections.- Basis of Susceptibility to Lung Infection.- Molecular Pathology of Viral Respiratory Diseases.- Molecular Pathology of Rickettsial Lung Infections.- Bacteria.- Immunopathology of Tuberculosis.- Molecular Pathology of Fungal Lung Infection.- Parasites.- Molecular Pathology of Other Nonneoplastic Pulmonary Diseases: General Principles.- Inflammation.- Oxidants and Antioxidants.- Epithelial Repair and Regeneration.- Fibrogenesis.- Stem Cells in Nonneoplastic Lung Disorders.- Gene Therapy in Nonneoplastic Lung Disease.- Molecular Pathology of Other Nonneoplastic Pulmonary Diseases: Specific Entities.- Smoking-Related Lung Diseases.- Heritable ?1-Antitrypsin Deficiency.- Asthma.- Cystic Fibrosis.- Pulmonary Organogenesis and Developmental Abnormalities.- Genetic Abnormalities of Surfactant Metabolism.- Usual Interstitial Pneumonia.- Sarcoidosis: Are There Sarcoidosis Genes?.- Histiocytic Diseases of the Lung.- Pulmonary Arterial Hypertension.- Immunopathology of Pulmonary Vasculitides.- Asbestosis and Silicosis.
| Erscheinungsdatum | 19.08.2017 |
|---|---|
| Reihe/Serie | Molecular Pathology Library ; 1 |
| Zusatzinfo | XXI, 682 p. |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 210 x 279 mm |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Pneumologie |
| Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
| Schlagworte | Asthma • Neoplastic • nonneoplastic • pulmonologist • thoracic surgeons |
| ISBN-10 | 1-4939-5040-1 / 1493950401 |
| ISBN-13 | 978-1-4939-5040-9 / 9781493950409 |
| Zustand | Neuware |
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