Biologic and Systemic Agents in Dermatology

Buch | Hardcover

XVII, 574 Seiten

2018 | 1st ed. 2018
Springer International Publishing (Verlag)
978-3-319-66883-3 (ISBN)

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Written by leading experts in the field and designed for dermatologists and residents, this book includes evidence-based medicine that underscores the clinical data, as well as practical tips on how to use both biologic and systemic agents in the field of dermatology. In the past decade, there have been several groundbreaking advances in medical dermatology. Novel biologic and systemic agents have been developed to treat inflammatory disorders, including psoriasis and atopic dermatitis, as well as skin malignancies such as melanoma.

Biologic and Systemic Agents in Dermatology encompasses these developments by describing the mechanism of action of these various agents and the clinical efficacy and safety to treating these respective disorders. The utilization of biologic and systemic agents in other dermatologic conditions, pharmacoeconomics, pharmacovigilance, and clinical trials outcomes are discussed as well as topics including tumor necrosis, conventional systemic agents for psoriatic disease, and oral agents for atopic dermatitis.

Paul S. Yamauchi, M.D., Ph.D. is Clinical Assistant Professor of Dermatology, David Geffen School of Medicine at UCLA and Harbor-UCLA Medical Center and isdermatologist in private practice at the Dermatology Institute and Skin Care Center in Santa Monica, California. Dr. Yamauchi is a fellow with the American Academy of Dermatology and the American Society of Dermatology Surgery and is also a member of the Los Angeles Metropolitan Dermatologic Society and California Society of Dermatology and Dermatologic Surgery. He is the editor-in-chief of Dermatology Reports and is the author and co-author of more than 70 publications, including several books. Dr. Yamauchi conducts numerous clinical research trials at the Clinical Science Institute in Santa Monica and serves as a principle investigator in several studies, including new therapies for psoriasis, skin cancer, eczema and acne, and has been a consultant for the development of new innovative therapies in dermatology. He is recognized as a key expert leader on psoriasis and has served on the Medical Board for the National Psoriasis Foundation and the Scientific Advisory Committee for the National Eczema Association. He has extensive experience using the new biologics, oral drugs, and topical medications in the treatment of psoriasis, and has been invited as a speaker at international, national, regional, and local venues to talk about new advances in the treatment of psoriasis and atopic dermatitis. In addition, he is a strong advocate in establishing patient support groups for psoriasis, and has published extensively in new advances in the treatment of psoriasis. Dr. Yamauchi has also spoken on other dermatologic conditions at national and local meetings and has published many peer-reviewed articles including acne, eczema, skin manifestations associated with rheumotologic conditions, and hyperhidrosis. He has given several television media interviews locally in Los Angeles as well as nationally on ESPN, national news, Inside Edition, and internet webcasts. In addition, he has been quoted several times in the Los Angeles Times, Los Angeles Daily News, Dermatology Times, Skin and Allergy News, and several magazines. He has been the recipient of many awards including Marquis Who's Who in Medicine and Healthcare, Super Doctors in Southern California, and America's Top Physicians List among others.

History of Therapies in Dermatology. Past to Present.- Validated scoring systems.- Interpreting Clinical Trial Data.- Compliance and Persistency.- Quality of Life in the Dermatology Practice.- Medical Legal Issues with Biologic Agents in the Treatment of Psoriasis .- Patient and Physician Perspectives on Traditional Systemic and Biologic Therapies for Psoriasis.- Outcomes of Comorbidities with Biologic and Systemic Agents .- Pharmacovigilance.- Pharmacoeconomics of Biologic Therapy in Dermatology.- Immunogenicity of Biologic Agents in Psoriasis .- Manufacturing of Biologics.- Tumor Necrosis Factor Inhibition .- Dual Inhibition of IL-12/IL- 23 and Selective Inhibition of IL-23 in Psoriasis.- Interleukin-17 Inhibition for the Treatment of Inflammatory Skin Disease.- Systemic Therapies in Psoriasis.- Nail, Scalp, and Palmoplantar Psoriasis.- Current and Emerging Treatments for Psoriatic Arthritis.- JAK Kinase Inhibitors in Dermatology.- Fumaric Acid Esters in Dermatology.- Phosphodiesterase Inhibitors for the Treatment of Inflammatory Skin Conditions.- Oral Retinoids in Dermatology.- Combination Therapy with Biologics and Other Systemic Treatments in Psoriasis.- Transitioning Biologic and Systemic Therapies in Psoriatic Patients.- Practical Considerations and Complex Cases in Psoriasis.- Biosimilars in Dermatology.- Biological Agents in Pediatric Dermatology.- Oral systemic Agents in Pediatric Dermatology.- Utilization of Biologic and Systemic Agents in the Elderly.- Miscellaneous Uses of Biologic and Systemic Agents in Other Dermatologic Conditions.- Biologics for the Treatment of Atopic Dermatitis.- Oral Agents for Atopic Dermatitis: Current and in Development.- Cutaneous T-cell lymphoma.- Anti-CD20 Agents and Potential Novel Biologics in Pemphigus Vulgaris and Other Autoimmune Blistering Diseases.- Oral Systemic Agents for Immunobullous Disorders .- Biologic and Systemic Agents in Hidradenitis Suppurativa.- Systemic and Biologic Agents for Lupus Erythematosus.- Anti-IgE Therapy in Dermatology.- Role of Intravenous Immunoglobulin in Dermatologic Disorders.- Systemic Antifungals.- Systemic Antivirals in Dermatology .- Antihelmintics in Dermatology.- Systemic Therapies for Scarring and Non-scarring alopecia.- Dapsone in Dermatology.- Systemic Non-Antibiotic Therapy in acne and rosacea.- Oral Antibiotics in Dermatology: A Practical Overview with Clinically Relevant Correlations and Management Suggestions.- Sonic Hedgehog Pathway Inhibition in the Treatment of Advanced Basal Cell Carcinoma.- Update in Immunotherapies for Melanoma.- Patient advocacy organizations.

Erscheinungsdatum	28.01.2018
Zusatzinfo	XVII, 574 p. 95 illus., 92 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	210 x 279 mm
Gewicht	1516 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
Schlagworte	Atopic dermatitis • biologic agents of dermatology • Dermatology • Medicine • Medicine: general issues • Psoriasis • Skin Malignancies • systemic dermatology
ISBN-10	3-319-66883-8 / 3319668838
ISBN-13	978-3-319-66883-3 / 9783319668833
Zustand	Neuware