Managing BRCA Mutation Carriers

Buch | Hardcover

XI, 242 Seiten

2017 | 1st ed. 2017
Springer International Publishing (Verlag)
978-3-319-59197-1 (ISBN)

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As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.

Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from amyriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

Anees B. Chagpar, MD, MSc, MPH, MA, MBA, FRCS(C), FACSAssociate Professor, Department of SurgeryDirector, The Breast Center -- Smilow Cancer Hospital at Yale-New HavenAssistant Director -- Global Oncology, Yale Comprehensive Cancer CenterYale University School of Medicine20 York Street, First floor Suite ANew Haven, CT 06510Phone: 203-200-1518

Risk Assessment for Breast Cancer.- Genetic Evaluation for Women at Increased Risk.- Imaging Screening and Surveillance.- Risk Reducing Surgery for BRCA1/2 Genetic Mutation Carriers.- Prophylactic Oophorectomy for Patients with Germline BRCA Mutations.- Pathology of BRCA Tumors.- Surgical Management of Breast Cancer in BRCA Mutation Carriers.- Medical Management of Breast Cancer in BRCA Mutation Carriers.- Radiation Oncology Considerations in the Management of Mutation Carriers with Breast Cancer.- Fertility Preservation in BRCA Carriers: Special Considerations.- Management of Male BRCA Mutation Carriers.- Psychosocial, Ethical, and Legal Implications for Mutation Carriers.

Erscheinungsdatum	03.08.2017
Zusatzinfo	XI, 242 p. 24 illus., 21 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	564 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Schlagworte	Adjuvant radiation therapy • children of BRCA carriers • DNA damage repair • Human genetics • medical genetics • Medicine • Medicine: general issues • Oncology • Pathology • Pathology of BCRA • Platinum-based agents • surgical oncology
ISBN-10	3-319-59197-5 / 3319591975
ISBN-13	978-3-319-59197-1 / 9783319591971
Zustand	Neuware