An Evidence Framework for Genetic Testing

Engineering National Academies of Sciences and Medicine, Health and Medicine Division, Board on Health Care Services, Board on the Health of Select Populations, Committee on the Evidence Base for Genetic Testing (Autoren)

Buch | Softcover

148 Seiten

2017
National Academies Press (Verlag)
978-0-309-45329-5 (ISBN)

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Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality.

Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.

Table of Contents

Front Matter
Summary
1 Introduction
2 Genetic Testing
3 Genetic Test Assessment
4 Evidence
5 An Evidence Framework for Genetic Testi
Appendix A: Understanding Genetic Variance and Phenotype Expression
Appendix B: The GETT Checklist
Appendix C: Using Evidence to Inform Clinical and Policy Decisions
References
Glossary

1 Front Matter; 2 Summary; 3 1 Introduction; 4 2 Genetic Testing; 5 3 Genetic Test Assessment; 6 4 Evidence; 7 5 An Evidence Framework for Genetic Testi; 8 Appendix A: Understanding Genetic Variance and Phenotype Expression; 9 Appendix B: The GETT Checklist; 10 Appendix C: Using Evidence to Inform Clinical and Policy Decisions; 11 References; 12 Glossary

Erscheinungsdatum	28.05.2017
Verlagsort	Washington
Sprache	englisch
Maße	216 x 279 mm
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	0-309-45329-1 / 0309453291
ISBN-13	978-0-309-45329-5 / 9780309453295
Zustand	Neuware