Human Genome Editing

Science, Ethics, and Governance

Engineering National Academies of Sciences and Medicine, National Academy of Medicine, National Academy of Sciences, Medical Committee on Human Gene Editing: Scientific and Ethical Considerations (Autoren)

Buch | Softcover

328 Seiten

2017
National Academies Press (Verlag)
978-0-309-45288-5 (ISBN)

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Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions.

Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Table of Contents

Front Matter
Summary
1 Introduction
2 Oversight of Human Genome Editing and Overarching Principles for Governance
3 Basic Research Using Genome Editing
4 Somatic Genome Editing
5 Heritable Genome Editing
6 Enhancement
7 Public Engagement
8 Summary of Principles and Recommendations
References
Appendix A: The Basic Science of Genome Editing
Appendix B: International Research Oversight and Regulations
Appendix C: Data Sources and Methods
Appendix D: Committee Member Biographies
Appendix E: Glossary

1 Front Matter; 2 Summary; 3 1 Introduction; 4 2 Oversight of Human Genome Editing and Overarching Principles for Governance; 5 3 Basic Research Using Genome Editing; 6 4 Somatic Genome Editing; 7 5 Heritable Genome Editing; 8 6 Enhancement; 9 7 Public Engagement; 10 8 Summary of Principles and Recommendations; 11 References; 12 Appendix A The Basic Science of Genome Editing; 13 Appendix B International Research Oversight and Regulations; 14 Appendix C Data Sources and Methods; 15 Appendix D Committee Member Biographies; 16 Appendix E Glossary

Erscheinungsdatum	11.10.2017
Verlagsort	Washington
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	0-309-45288-0 / 0309452880
ISBN-13	978-0-309-45288-5 / 9780309452885
Zustand	Neuware