Advances in Studies on Enzyme Inhibitors as Drugs

Volume 1: Anticancer & Antiviral Drugs

Buch | Hardcover

340 Seiten

2017
Nova Science Publishers Inc (Verlag)
978-1-5361-0504-9 (ISBN)

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This book which is edited by eminent scientist Satya P. Gupta, covers the most recent development on design and discovery of the most useful drugs acting against several life threatening diseases such as cancer, viral infections and many others in two volumes. All of these drugs are based on inhibitions of various enzymes. Most human diseases are found to be associated with the overexpression of the enzymes. The book presents the structural aspects of various enzymes, their active sites, and the structural requirements of chemicals for strong interactions with enzymes. Volume One contains twelve chapters related to enzyme inhibitors acting as anticancer and antiviral drugs (each written by highly acclaimed authors), and Volume Two contains ten chapters on enzyme inhibitors acting against miscellaneous diseases written by equally competent authors. The book may be an asset for drug industries, research organisations, and individual researchers.

Preface; Mitogen-Activated Protein Kinase (MAPK) Inhibitors for The Treatment of Advanced Hepatocellular Carcinoma; Protein Farnesyltransferase Inhibitors as Novel Anticancer Chemotherapeutics; Peptidylarginine Deiminase (PAD) Inhibitors; Interfering with Enzymatic Steps of Micrornas Pathway Using Small Molecules; In Silico Studies for the Discovery of Leads to Inhibit Cyclin-Dependent Kinase 2 (CDK2); Design & Development of Tyrosine Kinase Inhibitors as Anticancer Drugs; In Silico Design of Carbonic Anhydrase Inhibitors as Antitumor Drugs; Studies on Inhibitors of Dengue Virus Protease; Design & Development of Inhibitors of Picornavirus Proteases; Neuraminidase Inhibitors: From Research Tools to Drug Candidates; Recent Developments in HIV-1 Integrase Inhibitors; Studies on Dual Inhibitors of HIV Reverse Transcriptase & Integrase; Index.

Erscheinungsdatum	05.01.2017
Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	818 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pflege
	Medizin / Pharmazie ► Pharmazie ► PTA / PKA
ISBN-10	1-5361-0504-X / 153610504X
ISBN-13	978-1-5361-0504-9 / 9781536105049
Zustand	Neuware