Cutaneous Melanoma
Lippincott Williams and Wilkins (Verlag)
978-0-397-51052-8 (ISBN)
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This book describes the modalities of treatment used in clinical management such as surgery, radiation and biological therapy and chemotherapy for all stages of disease. The treatment chapters follow a description of the biology of melanoma - epidemiology, genetics, tumour biology and immune response. Information from the treatment of over 20,000 cases around the world is incorporated, providing data on diagnosis and pathologic examinations. Natural history, prognosis and treatment results are supported by statistical data and new chapters are provided on such topics as dysplastic nevus syndrome, melanoma and pregnancy, biologic therapy, plastic surgical repairs, childhood melanomas, head and neck melanomas and subungual melanomas.
Part 1 Epidemiology, etiology and biology: the history of melanoma from Hunter to Handley (1787-1907); epidemiologic studies; the worldwide incidence of malignant melanoma; changing trends in the clinical and pathologic features of melanoma; ultraviolet radiation and other putative causes of melanoma; the dysplastic nevus as precursor and market of increased risk for melanoma; screening for melanoma; biology of melanocytes and melanoma; the genetics of human cutaneous malignant melanoma; cytogenetics of human malignant melanoma; the biology of melanoma metastasis; melanoma antigens; immune responses to melanoma. Part 2 Predictive factors of melanoma outcome: an analysis of prognostic factors in 8500 patients with cutaneous melanoma; a comparison of prognostic factors worldwide; a computerized mathematical model and scoring system for predicting outcome in patients with localized melanoma; classification and staging. Part 3 Primary melanoma: clinical characteristics; histopathology of malignant melanoma and its precursor lesions; biopsy of melanoma; surgical treatment of primary melanoma; plastic surgical repairs of melanoma defects; local recurrences and their management; head and neck melanoma; melanoma of the hand and foot (volar and subungal melanoma); childhood melanoma; melanoma and pregnancy; mucosal melanoma. Part 4 Regional metastases: general principles of regional lymphadenectomy; elective lymph node dissection - pros and cons; defining lymphatic drainage patterns with cutaneous lymphoscintigraphy; cervical and parotid node dissections; axilliary lymph node dissection; groin dissection; hyperthermic regional perfusion for melamnoma of the limbs; recurrent regional metastases and their management. Part 5 Distant metastases: diagnosis of metastatic melanoma at distant sites; treatment for advances melanoma; chemotherapy for metastatic melanoma; radiotherapy for melanoma; biologic therapy for melanoma; melanoma vaccines; care of the dying patient.
| Erscheint lt. Verlag | 1.12.1991 |
|---|---|
| Zusatzinfo | 379 illustrations, 136 tables, 27 colour plates |
| Verlagsort | Philadelphia |
| Sprache | englisch |
| Maße | 204 x 254 mm |
| Gewicht | 1720 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| ISBN-10 | 0-397-51052-7 / 0397510527 |
| ISBN-13 | 978-0-397-51052-8 / 9780397510528 |
| Zustand | Neuware |
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