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Gastrointestinal Motility

Proceedings of the 9th International Symposium on Gastrointestinal Motility Held in Aix-En-Provence, France, September 12-16, 1983

Claude Roman (Herausgeber)

Buch | Hardcover
648 Seiten
1983 | 1984 ed.
Kluwer Academic Publishers (Verlag)
978-0-85200-745-7 (ISBN)
CHF 119,75 inkl. MwSt
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This volume reviews the most recent knowledge in the field of gastrointestinal motility in health and disease. The topics addressed include basic as well as clinical data concerning the motor functions of the entire gut: the lower oesophageal sphincter and the gastro-oesophageal reflux; the gastric emptying and the role of the pylorus; the motility of the biliary tract and its disorders; the cyclic motor activity of the gut and intestinal transit; the colonic and ano-rectal motility. There are also impOltant contributions in physiology and pharmacology relating to the neurohumoral regulation of the gut, and the function of digestive smooth muscle. Several papers explore the nature of the linkage between brain and gut. a link which has long been deduced by clinicians but not, until recently, systematically explored by scientists. The individual papers, selected from a large number of submissions, have been subject to 'peer-review' by an inter- national committee which includes both cliniCians and basic scientists.
Therefore this book should serve as an up to date source of information for researchers concerned with basic sciences as well as for clinicians in gastroenterology, medicine and surgery. C. Roman v This volume is dedicated to the memory of two friends and colleagues: Professor Dr J. HELLEMANS Professor Dr H. MONGES Acknowledgments This was the 9th of this series of symposia held alternatively in Europe and North America, and the first to be held in France.

Section 1 Oesophagus, Lower Oesophageal Sphincter.- 1 Effects of the vagal deafferentation on oesophageal motility in the conscious sheep.- 2 Electrophysiological and pharmacological characterization of the NANC nerve mediated inhibition of the circular muscle layer of the opossum esophagus.- 3 The edrophonium response : use in diagnosis and possible understanding of mechanisms of esophageal chest pain.- 4 The diabetic esophagus - revisited.- 5 Abnormalities of esophageal motor function in diabetic patients.- 6 In vitro study of the effects of Leu-enkephalin and related drugs on the vagally induced responses of the cat lower esophageal sphincter.- 7 Relation between lower esophageal sphincter pressure and plasma concentration of neurotensin(1-13) during intravenous infusion of neurotensin (1-13) and (Gln4-neurotensin(1-13) in man.- 8 d-Pro2, d-Trp7,9 substance P: an effective antagonist of exogenous and endogenous substance P.- 9 Relationship of functional changes to structural changes in megaesophagus of Chagas' disease.- 10 Developmental characteristics of the kitten lower esophageal sphincter.- 11 Variability of pressure and myoelectrical activity recorded from the lower esophageal sphincter of fasted conscious opossums.- 12 Reflux characteristics in health and disease.- Section 2 Gastric Motility and Emptying.- 13 Effect of dopamine or dopamine blocker on the antral motility in isolated perfused rat stomach.- 14 Dual effect of substance P on canine antral muscle.- 15 Regulation of gastric antral slow wave frequency by prostaglandins.- 16 Mechanical activity of isolated human pyloric muscle, in comparison with canine pylorus.- 17 Stimulating effects of cisapride on antroduodenal motility in the conscious dog.- 18 Changes in the innervation of the fundus after subtotal gastrectomy.- 19 Studies on the process of gastric emptying.- 20 The timing of pyloric closure in man: studies with impedence electrodes.- 21 Effect of nervous stimulation on pyloric resistance and configuration.- 22 Small intestinal regulation of gastric emptying.- 23 Vagal osmosensitive receptors located in the small intestine. Role in gastric emptying.- 24 Gastric emptying in asymptomatic partial gastrectomy (B-II) patients.- 25 Effects of bombesin on gastric emptying of solids in normal and antrectomized subjects: evidence for an action at the distal stomach.- 26 Involvement of endogenous opiates in radiation-induced suppression of gastric emptying.- 27 Gastrointestinal contractile activity associated with vomiting in the dog.- 28 Vagal control of gastrointestinal tract during vomiting.- Section 3 Biliary Tract.- 29 Enkephalins mediate cholecystokinin-induced gallbladder contraction in the guinea pig.- 30 Intramural innervation of the opossum sphincter of Oddi.- 31 The relationship between gastrointestinal cyclic motor activity and gallbladder emptying in humans.- 32 Defective gallbladder contractility associated with increased bile lithogenicity in ground squirrels and prairie dogs.- 33 Prostaglandins modulate human gallbladder motility.- 34 Fasting canine biliary secretion and the sphincter of Oddi.- 35 Stomach motility modulates bile flow in the pig.- Section 4 Small Intestine and Migrating Myoelectric Complexes.- 36 Effects of peptide YY and porcine pancreatic polypeptide on migrating myoelectric complexes in the rat small intestine.- 37 Motilin release and the migrating myoelectric complexes.- 38 Motilin and myoelectric complexes in the pig.- 39 Somatostatin induces ectopic activity fronts of the migrating motor complexes via a local intestinal mechanism.- 40 Morphine initiated migrating myoelectric complexes in postprandial state in dog: changes in refractoriness of MMC mechanism.- 41 The effect of morphine on motility, flow and transit in the human ileocolonic junctional region.- 42 Blockade of migrating myoelectric complexes by naloxone.- 43 Effect of intraduodenal bile on myoelectric activity of the upper gastrointestinal tract and sphincter of Oddi.- 44 Nocturnal motor activity of the upper gastrointestinal tract, and plasma levels of entero-pancreatic hormones and primary bile acids in man.- 45 The development of fasting small intestinal motility in the human neonate.- 46 Feeding behaviour and the migrating myoelectric complex.- 47 Does exercise affect the migrating motor complex in man?.- 48 Sham feeding amplifies the secretory component of interdigestive activity.- 49 Jejunal motility in dystrophia myotonica: a manometric study of migrating motor complex.- 50 Modification of the interdigestive migrating motor complex in patients with partial gastrectomy and gastrojejunostomy.- 51 Disorganisation of the interdigestive small bowel motility by E. coli endotoxin in the rat.- 52 Abnormal gastrointestinal motility in diabetics and after vagotomy.- 53 Stimulation of action potential complexes by fluid distension of rabbit small intestine - evidence that migrating action potential complexes are a non-specific myoelectric response.- 54 Electrical activity of an intrinsically denervated jejunum of the unanesthetized rat.- 55 Evidence for a muscarinic inhibitory brake activated by peptides in the canine small intestine.- 56 The ileal brake: a potent mechanism for feedback control of gastric emptying and small bowel transit.- 57 Comparison of neurotensin and fat On myoelectric activity of the small bowel.- 58 Modulation of rat small bowel motor activity by food and peptides.- 59 Dose-dependent effects of ceruletide on jejuna) motor activity and on experimentally induced pain in healthy humans.- 60 Indomethacin-induced spiking activity in rabbit ileum: in vivo interactions of prostaglandins and cholinergic neurotransmission.- 61 Electrical activity of cat intestine following defunctionalization.- 62 Vagal and splanchnic influences on small intestinal motility in the anaesthetized ferret.- Section 5 Lower Digestive Tract.- 63 Relationship between contractile and intracellular electrical activities in canine colon muscle layers.- 64 Modulation of pacemaker activity in circular muscle of the canine colon.- 65 Longitudinal and circular muscle of canine colon have different and characteristic electrical and mechanical activities.- 66 The relationship between extracellular and intracellular slow waves.- 67 The electrical basis for the inhibitory response of the guinea pig internal anal sphincter to nerve stimulation and drugs.- 68 Effects of salicylic acid (SA) and aspirin (ASA) on met-enkephalin (FK) and acetylcholine (ACH) stimulated motility of the isolated rat colon.- 69 Effect of leu-enkephalin on synaptic transmission in the inferior mesenteric ganglion.- 70 Effects of trimebutine (TMB) on spontaneous electrical activity and on junction potentials evoked by parasympathetic nerve stimulation in cat and rabbit colon.- 71 Food increases the propagating myoelectric spiking activity in the human colon.- 72 Effects of the pancreatic polypeptide, NPY and PYY in relation to sympathetic influence on colonic motility and blood flow.- 73 Ultrasound used to measure the response of colonic motility to essential oils.- 74 Nervous reflexes involved in the co-ordination of the motility of internal anal sphincter and urinary bladder.- 75 Relaxations of the internal anal sphincter elicited by rectal and extrarectal distensions in man.- 76 Rectal function in patients with idiopathic chronic constipation.- 77 Severe, idiopathic constipation is caused by a distinct abnormality of the colonic myenteric plexus.- 78 Physiological study of the lower digestive tract in primary constipation.- 79 Intestinal transit time is related with different anorectal motility patterns in chronic non-organic constipation.- 80 Is incontinence in diabetes mellitus due to diabetic autonomous neuropathy?.- Section 6 Smooth Muscle, Nervous and Hormonal Control.- 81 Correlation between the electrical properties and morphological characteristics in the smooth muscle cells during culture.- 82 Interstitial cells of Cajal (ICC): selective uptake of methylene blue inhibits slow wave activity.- 83 The mechanism of action of pentagastrin on circular muscle from canine gastric corpus.- 84 Role of bombesin in muscularis mucosa of canine colon.- 85 Effect of substance P on non-cholinergic post-stimulus depolarization of the circular smooth muscle of the guinea pig ileum.- 86 Gastrointestinal motility stimulating properties of cisapride, a non-antidopaminergic non-cholinergic compound.- 87 Characterization of 125I-Trp11-neurotensin binding to rat fundus smooth muscle plasma membranes.- 88 Facilitation and inhibition by 5-hydroxytryptamine and R 51 619 of acetylcholine release from guinea pig myenteric neurons.- 89 The interaction of adenosine with isolated myenteric nerve varicosities.- 90 Effect of peptide YY on contractile activity in the stomach of Heidenhain pouch dogs.- 91 Alterations of digestive motility by Escherichia coli endotoxin in rabbits mediated through central opiate receptors.- 92 Central effects of thyrotropin-releasing hormone on gastrointestinal motility in fasted and fed rats.- 93 The brain-gut axis: a physiological model.- 94 Spinal, supraspinal and peripheral sites of opioid intestinal actions.- 95 Centrally-administered bombesin delays small intestinal transit but stimulates motility in the rat.- 96 Effects of hindbrain l-glutamic acid application on gastrointestinal motor function in the cat.- LECTURE: Gastrointestinal hormones and intestinal motility.

Zusatzinfo 81 black & white illustrations, biography
Verlagsort Dordrecht
Sprache englisch
Maße 150 x 230 mm
Gewicht 1220 g
Themenwelt Medizinische Fachgebiete Innere Medizin Gastroenterologie
ISBN-10 0-85200-745-0 / 0852007450
ISBN-13 978-0-85200-745-7 / 9780852007457
Zustand Neuware
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