Gene- and Cell-Based Treatment Strategies for the Eye

Buch | Softcover

VII, 95 Seiten

2016 | 1. Softcover reprint of the original 1st ed. 2015
Springer Berlin (Verlag)
978-3-662-52329-2 (ISBN)

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In this book, leading experts provide detailed descriptions of the exciting treatments that are expected to become part of the ophthalmologist's arsenal within the next 10-20 years. The treatments discussed relate to a wide variety of conditions, including macular degeneration, Leber's congenital amaurosis, retinitis pigmentosa, choroideremia, and retinoschisis. The authors explain clearly how different gene and cell therapies work and provide first-hand accounts of the difficulties that they have faced in bringing these technologies to clinical trial, such as issues relating to funding and ownership. Results achieved to date are presented, and the further steps required before the treatment in question can become a routine option are considered. Gene- and Cell-Based Treatment Strategies for the Eye is unique in showing the organic development of cutting-edge science into potential treatments for eye disease without compromising on accurate reporting of scientific facts. It will persuade the average practitioner or researcher - whether ophthalmologist, health worker, or scientist - that change is indeed coming and is not just a hollow promise of the tabloid media.

Introduction.- Gene Therapy for Leber's Congenital Amaurosis due to RPE65 Mutations.- Gene Therapy for Choroideremia.- Gene Therapy for Dominantly Inherited Retinal Degeneration.- Age-Related Macular Degeneration: The Challenges.- Neovascular Age Related Macular Degeneration: Secretion Gene Therapy.- Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium for the Treatment of Macular Degeneration.- Restoring Physiologic Barriers Against Neovascular Invasion.

Erscheinungsdatum	14.10.2016
Reihe/Serie	Essentials in Ophthalmology
Zusatzinfo	VII, 95 p. 30 illus., 22 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Augenheilkunde
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
Schlagworte	Complex eye diseases • corneal disease • gene therapy • Human genetics • medical genetics • Medicine • Medicine: general issues • Ophthalmology • Retinal Disease • Stem Cells
ISBN-10	3-662-52329-9 / 3662523299
ISBN-13	978-3-662-52329-2 / 9783662523292
Zustand	Neuware