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Microarray Bioprinting Technology

Fundamentals and Practices

Moo-Yeal Lee (Herausgeber)

Buch | Hardcover
XIII, 175 Seiten
2017 | 1st ed. 2016
Springer International Publishing (Verlag)
978-3-319-46803-7 (ISBN)

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This book introduces key fundamentals of microarray bioprinting, including the required chip platforms and associated instruments/devices, experimental protocols for cell printing and biochemical- and cell-based assays, and several example applications. Various bioprinting approaches that allow for the rapid testing of hundreds of different cell culture conditions in combinations on a single chip are discussed in detail. Also covered is high-content, 3D cell-based imaging assays of tissue functions on miniaturized tissue constructs for high-throughput, predictive screening of drug efficacy and toxicity. This is an ideal book for graduate and postgraduate students in the field of biomedical engineering as well as scientists in the pharmaceutical industry.

This book also:

  • Broadens readers' understanding of the principles of microarray bioprinting, chip platforms and associated instruments/devices, and surface chemistry for micropatterning of cells on the chip platform
  • Covers the latest developments in printing cells in hydrogels and methods of gelation as well as printing other biological samples in aqueous solutions
  • Illustrates the complete process for cell staining and high-content imaging of 3D cells on the chip and predicting human metabolism and toxicology on the chip

Dr. Moo-Yeal Lee is an Assistant Professor at Cleveland State University in the Department of Chemical & Biomedical Engineering.

1. Overview of Microarray Bioprinting Technology.- 2. Microarray Spotter and Printing Technologies.- 3. Chip Platforms and Chip Surface Treatments.- 4. Biological Sample Printing.- 5. High Content Cell Staining.- 6. 3D-Cultured Cell Image Acquisition.- 7. High-Content Image Analysis.- 8. Applications of Microarray Bioprinting.

Erscheinungsdatum
Reihe/Serie SpringerBriefs in Bioengineering
Zusatzinfo XIII, 175 p. 120 illus., 114 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Biomedizin
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Naturwissenschaften Chemie Technische Chemie
Schlagworte Applications of Microarray Bioprinting • Assay Miniaturization • biomedical engineering • Cell Printing in Hydrogels • cellular biology (cytology) • Engineering • Fabrication of Microarray Biochips • High-Content Imaging of 3D Cells on Chip • Hydrogels for Cell Encapsulation • Industrial chemistry and chemical engineering • Metabolism-Induced Toxicity Assays • Microarray Bioprinting • Microarray Bioprinting Technology • Microarray Spotting Technology • microengineering • Micropillar/Microwell Chip • Miniaturized 3D Bioprinting • Miniaturized 3D Cell Cultures • Printing Biological Samples on Chip • Regenerative Medicine/Tissue Engineering • Stem Cell Cultures and Toxicity Assays
ISBN-10 3-319-46803-0 / 3319468030
ISBN-13 978-3-319-46803-7 / 9783319468037
Zustand Neuware
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