Biotechnology and Human Genetic Predisposition to Disease
John Wiley & Sons Inc (Verlag)
978-0-471-56772-1 (ISBN)
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This work describes the remarkable developments in the detection of inherited or acquired genetic mutations. Focusing on the advances in DNA technology, the book examines new methods for large-scale genome mapping, DNA sequencing and protein structure analysis. The progress of molecular diagnostics in revealing significant human disease genes and in understanding DNA damage and repair is also discussed in the state-of-the-art work. Significant discussions underscore the pervasive and powerful influence of the polymerase chain reaction in all areas of DNA manipulation and analysis.
EXPLORATION OF THE HUMAN GENOME: The Sex- Determining Function of the Human Y Chromosome; A Comprehensive Gene Order for Human Chromosome 19q; DETECTION AND ANALYSIS OF HUMAN GENETIC DISEASES: Identification and Screening for Phenylketonuria Mutations by Polymerase Chain Reaction; Simplified Diagnosis of New Mutation X-Linked Disease; Eco-Genetics of Chemical Carcinogens; STEPS TOWARD GENE THERAPY: Germ Line Correction of OTC Deficiency in Spf Mice; Human Adenosine Deaminase Expression in the Progeny of Murine Hematopoietic Stem Cells; DNA DAMAGE AND REPAIR: Role of Gene Expression in the Fine Structure of DNA Damage Processing; Nucleotide Excision Repair in the Yeast Sacchsromyces Cerevisiae: Beyond the Cloned Genes; Mutagenesis of a UV Irradiated Shuttle Vector Plasmid in Repair of Proficient and Deficient Human Cells: The Hotspot Problem; NEW METHODS OF DNA ANALYSIS: Direct Isolation of Expressed Sequences from Defined Chromosomal Regions; A Rapid Chemical Cleavage Method for the Detection and Localization of Base Changes in RNA and DNA.
| Reihe/Serie | UCLA Symposia on Molecular and Cellular Biology, New Series ; Vol 126 |
|---|---|
| Zusatzinfo | Ill. |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 35 x 55 mm |
| Gewicht | 595 g |
| Themenwelt | Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik |
| Technik ► Umwelttechnik / Biotechnologie | |
| ISBN-10 | 0-471-56772-8 / 0471567728 |
| ISBN-13 | 978-0-471-56772-1 / 9780471567721 |
| Zustand | Neuware |
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