Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Buch | Softcover

436 Seiten

2016 | Softcover reprint of the original 1st ed. 2014
Springer-Verlag New York Inc.
978-1-4939-5501-5 (ISBN)

Artikel merken

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.

Part I: Basic Concepts Underlying the Microbiota-Gut-Brain Axis.- Microbial Endocrinology and the Microbiota-Gut-Brain Axis.- Utilizing “omics” Tools to Study the Complex Gut Ecosystem.- The Enteric Nervous System and Gastrointestinal Innervation: Integrated Local and Central Control.- Intestinal Barrier Function and the Brain-Gut Axis.- Vagal Pathways for Microbiome-Brain-Gut Axis Communication.- The Brain-Gut Axis in Health and Disease.- Part II: Mechanistic Factors Influencing the Microbiota-Gut-Brain Axis.- Gastrointestinal Hormones and Their Targets.- Microbiome, HPA Axis and Production of Endocrine Hormones in the Gut.- Neuropeptides and the Microbiota‑Gut‑Brain Axis.- Bacterial Neuroactive Compounds Produced by Psychobiotics.- Multidirectional Chemical Signalling Between Mammalian Hosts, Resident Microbiota, and Invasive Pathogens: Neuroendocrine Hormone-Induced Changes in Bacterial Gene Expression.- Influence of Stressor-Induced Nervous System Activation on the Intestinal Microbiota and the Importance for Immunomodulation.- Part III: The Microbiota-Gut-Brain Axis in Health and Disease.- The Effects of Inflammation, Infection and Antibiotics on the Microbiota-Gut-Brain Axis.- Microbiota, Inflammation and Obesity.- Microbiota, Immunoregulatory Old Friends and Psychiatric Disorders.- Microbiota-Gut-Brain Axis and Cognitive Function.- The Impact of Microbiota on Brain and Behavior: Mechanisms & Therapeutic Potential.- Neuroimaging the Microbiome-Gut–Brain Axis.- The Future of Probiotics for Disorders of the Brain-Gut Axis.- Index.

Erscheinungsdatum	22.09.2016
Reihe/Serie	Advances in Experimental Medicine and Biology ; 817
Reihe/Serie	Microbial Endocrinology
Zusatzinfo	19 Illustrations, color; 29 Illustrations, black and white; XVIII, 436 p. 48 illus., 19 illus. in color.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Disease • microbial endocrinology • microbiome • Physiology
ISBN-10	1-4939-5501-2 / 1493955012
ISBN-13	978-1-4939-5501-5 / 9781493955015
Zustand	Neuware