Chordomas

Technologies, Techniques, and Treatment Strategies

M. Necmettin Pamir, Ossama Al-Mefty, Luis Borba (Herausgeber)

Buch | Hardcover

256 Seiten

2017
Thieme Medical Publishers Inc (Verlag)
978-1-62623-159-7 (ISBN)

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A rare form of cancer, chordomas are among the most difficult tumors to treat, requiring highly specialized training and surgical expertise.

Although generally slow-growing, chordomas present resection challenges due to their proximity to critical structures including the spinal cord, brainstem, nerves, and arteries.

Written by an impressive cadre of internationally-renowned experts, this textbook is the most current, concise, and definitive resource on diagnosis and management of this complex pathology. Acclaimed surgeons from Brazil, Canada, Japan, Turkey, the USA, and the UK are contributors.

The book starts with a historical overview, epidemiology, molecular pathogenesis, cytogenetics, local invasion and metastasis, and pathology. A thorough discussion covers diagnostic radiological and radionuclide imaging such as MRI, PET; SPECT, PET-CT, and PET-MRI, and clinical traits of skull base and spinal chordomas as defined by imaging modalities. Subsequent chapters explore decision making including selecting the most optimal techniques, surgical procedures, specialized topics, and new horizons in chordoma treatment.

Key Highlights:

Anterior and anterolateral approaches to the clivus
The use of endoscopy and intraoperative assistive technologies
Midline subfrontal, middle fossa, extended petrosal, and transcondylar approaches
Craniospinal fusion techniques following resection
Surgery for spinal chordomas from the cervical to the sacral region
Special topics such as radiation, proton beam therapy, Gamma-Knife radiosurgery, and pediatric chordomas and chondrosarcomas

This is an essential text for neurosurgeons, orthopedic spine surgeons, otolaryngologists, and radiation oncologists. Read and learn from innovators who have mastered the latest state-of-the-art treatment methodologies for chordomas.

Director, Skull Base Program, Lecturer, Harvard Medical SchoolDepartment of Neurosurgery, Brigham and Womens Hospital, Lecturer, Harvard School of Medicine, Boston, MA

Part I Definition, History, Demographics, Pathology, and Pathogenesis

1 Historical Aspects

2 The Descriptive Epidemiology of Chordomas

3 Evolutionary Origin of the Notochord

4 Molecular Biology of Chordomas

5 Cytogenetics of Chordomas

6 Local Invasion and Metastasis

7 Pathology

8 Experimental Models of Chordomas

Part II Diagnosis of Chordomas

9 Radiologic Findings and Differential Diagnosis of Chordomas at the Skull Base

10 Radiologic Findings and Differential Diagnosis of Chordomas in the Spine

11 Molecular Imaging of Chordomas

Part III Surgical Treatment of Chordomas

12 Surgical Decision Making in Chordomas

13 Choice of the Optimal Surgical Approach for Skull Base Chordomas

14 Anterior Approaches to the Clivus

15 Endoscopic Approaches for Skull Base Chordomas

16 Frontobasal Approaches for Skull Base Chordomas

17 Cranio-Orbital-Zygomatic Approach for Chordomas

18 Epidural Middle Fossa Approaches

19 The Extended Petrosal Middle Fossa Approach

20 The Transcondylar Approach to the Clivus

21 Craniovertebral Reconstruction after Chordoma Resection

22 Surgery for Spinal Chordomas

23 Intraoperative Assistive Technologies for Chordoma Surgery

Part IV Special Topics in Chordomas

24 Chordomas: A Personal Perspective

25 Radiation Treatment for Chordomas

26 Charged Particle Beams in Management of Clival Chordomas

27 Stereotactic Radiosurgery for Chordomas

28 Recurrence in Skull Base Chordomas and its Management

29 Outcome and Quality of Life of Patients with Chordomas

30 Chordomas and Chondrosarcomas in the Pediatric Population

31 Future Prospects in the Treatment of Skull Base Chordomas

Erscheinungsdatum	11.01.2017
Zusatzinfo	400 Illustrations
Verlagsort	New York
Sprache	englisch
Gewicht	2 g
Einbandart	gebunden
Themenwelt	Medizinische Fachgebiete ► Chirurgie ► Neurochirurgie
	Medizinische Fachgebiete ► Chirurgie ► Unfallchirurgie / Orthopädie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Orthopädie
Schlagworte	Chordomas • Krebs (Krankheit) • Krebs (Krankheit) / Karzinom • Neoplasie • Neurochirurgie • Tumor
ISBN-10	1-62623-159-1 / 1626231591
ISBN-13	978-1-62623-159-7 / 9781626231597
Zustand	Neuware