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Vascular Engineering (eBook)

New Prospects of Vascular Medicine and Biology with a Multidiscipline Approach
eBook Download: PDF
2016 | 1st ed. 2016
VI, 401 Seiten
Springer Japan (Verlag)
978-4-431-54801-0 (ISBN)

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This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions - atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction - has generated a focus on developing expertise to both maintain and treat the vascular system. 

As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.



KazuoTanishita: Waseda University Research Organization for Nano & Life Innovation
Kimiko Yamamoto: Department of Biomedical Engineering, The University of Tokyo


This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions - atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction - has generated a focus on developing expertise to both maintain and treat the vascular system. As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.

KazuoTanishita: Waseda University Research Organization for Nano & Life InnovationKimiko Yamamoto: Department of Biomedical Engineering, The University of Tokyo

Chapter 1 IntroductionChapter 2 Fundamentals of Vascular Bio-fluid and Solid MechanicsChapter 3 Fundamentals of Physiology and Biology of Vascular SystemChapter 4 Hemodynamics in Physio- and Pathological VesselsChapter 5 Cyclic Stretch-Induced Reorganization of Stress Fibers in Endothelial CellsChapter 6 Mechanical Characterization of Vascular Endothelial Cells Exposed to Fluid Shear StressChapter 7 Tensile Properties of Smooth Muscle Cells, Elastin, and Collagen FibersChapter 8 Mechanobiology of Endothelial Cells Related to the Formation of Arterial DiseaseChapter9 Mechanotransduction of Shear Stress by the EndotheliumChapter 10 Mechanobiology of Endothelial Cells Related to the Pathogenesis of Arterial DiseaseChapter 11 Vascular Engineering of Blood CoagulationChapter 12 Vascular Engineering to Make Blood-Compatible SurfaceChapter 13 Vascular Engineering of Circulatory Assist DevicesChapter 14 Innovations in Measuring Cellular MechanicsChapter 15 Innovation of Vascular Engineering by Mechano-medicineChapter 16 Integrated Vascular Engineering: Vascularization of Reconstructed TissueChapter 17 Novel Technology to Assay the Multicellular Network: On-Chip Cellomics Technology

Erscheint lt. Verlag 17.3.2016
Zusatzinfo VI, 401 p. 184 illus., 103 illus. in color.
Verlagsort Tokyo
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie
Technik Bauwesen
Schlagworte atherosclerosis • biomaterials • Endothelium • hemodynamics • Regeneration • Vascularization
ISBN-10 4-431-54801-7 / 4431548017
ISBN-13 978-4-431-54801-0 / 9784431548010
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