Cell Therapy for Perinatal Brain Injury

Haruo Shintaku, Akira Oka, Makoto Nabetani (Herausgeber)

Buch | Hardcover

150 Seiten

2018 | 1st ed. 2018
Springer Verlag, Singapore
978-981-10-1411-6 (ISBN)

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This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction.

These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world.

The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Disease will offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to furtherexplore this evolving therapy.

Haruo ShintakuDepartment of Pediatrics,Osaka City University Graduate School of Medicine,OsakaJapan Akira OkaDepartment of Pediatrics,University of Tokyo, TokyoJapan Makoto Nabetani, Department of Pediatrics,Yodogawa Christian Hospital, Osaka,Japan

1. Clinical trial of autologous cord blood cell therapy for neonatal hypoxic‐ischemic encephalopathy (HIE).- 2. New strategy of clinical studies for premature babies with ischemic brain damage .- 3. Pathophysiology and pathology of neonatal hypoxic-ischemic encephalopathy.- 4. Neural stem/progenitor cells for perinatal brain injury.- 5. Hematopoietic stem cells for perinatal brain injury.- 6. Umbilical cord-derived mesenchymal stromal cells for perinatal brain injury.- 7. Other tissues-derived mesenchymal stem cells for perinatal brain injury.- 8. CD34+ cell in cord blood and neonates.- 9. The History of Hypothermia therapy for perinatal ischemic brain injury.- 10. Clinical Procedure of Cell Therapy (Cord blood collection).- 11. Clinical Procedure of Cell Therapy (Separation and infusion).- 12. Cell therapy for adult infarction.- 13. Clinical trials on cell therapy for perinatal brain injury: Challenges and opportunities.- 14. A new prospective cell therapy for neonatal brain injury.

Erscheinungsdatum	28.03.2018
Zusatzinfo	XII, 150 p.
Verlagsort	Singapore
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Gesundheitsfachberufe ► Hebamme / Entbindungspfleger
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Gynäkologie / Geburtshilfe
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pädiatrie
	Medizin / Pharmazie ► Studium
Schlagworte	CD34 cell • clinical trial • Ischemic disease • mesenchymal stem cell • Neural stem cell • Stem Cell Therapy
ISBN-10	981-10-1411-6 / 9811014116
ISBN-13	978-981-10-1411-6 / 9789811014116
Zustand	Neuware