Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Volume 10

Buch | Hardcover

370 Seiten

2016
Academic Press Inc (Verlag)
978-0-12-805421-5 (ISBN)

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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis.

This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy.

Dr. Hayat has published extensively in the fields of microscopy, cytology, immunohistochemistry, immunocytochemistry, and antigen retrieval methods. He is Distinguished Professor, Department of Biological Sciences, Kean University, Union, New Jersey, USA.

I. Molecular Mechanisms Chapter 1. Overview of Autophagy Chapter 2. Molecular Mechanisms Underlying the Degradation of Peroxisomes Chapter 3. Role of Poly (ADP-Ribose) in Catalyzing Starvation-Induced Autophagy Chapter 4. Cross-Talk Between Autophagy and Death Receptor Signaling Pathways Chapter 5. Role of Autophagy in Mammalian Embryogenesis: Response to Developmental Programs Chapter 6. Autophagy in Adipose Tissue Chapter 7. Prevention of Adverse Metabolic Consequences of Adipocyte Dysfunction Using MR Antagonists Chapter 8. A Rapid Method for Detecting Autophagy Activity in Live Cells Using Cellometer Image Cytometry

II. Role in Disease Chapter 9. CDC37: Implications in Regulation of Kinases and Proteins Linked to Neurodegenerative and Other Diseases Chapter 10. Autophagy in the Degeneration of Optic Nerve and Spinal Cord Axons Chapter 11. Membrane Type-1 Matrix Metalloproteinase-Regulated Autophagy: A Role in Brain Cancer Chemoresistance Chapter 12. Induction of Autophagy and Apoptosis in Melanoma Treated with Palladacycle Complexes Chapter 13. Autophagy in Atherosclerosis

Erscheinungsdatum	05.07.2016
Verlagsort	San Diego
Sprache	englisch
Maße	191 x 235 mm
Gewicht	970 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
ISBN-10	0-12-805421-2 / 0128054212
ISBN-13	978-0-12-805421-5 / 9780128054215
Zustand	Neuware